2020
DOI: 10.1001/jama.2020.4958
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Community Prevalence of SARS-CoV-2 Among Patients With Influenzalike Illnesses Presenting to a Los Angeles Medical Center in March 2020

Abstract: Until recently, diagnostic testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (COVID-19), was only available through public health laboratories. [1][2][3] This limited testing was prioritized for persons who had severe illness or identifiable risk factors, such as travel to an area with ongoing transmission. Thus,

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Cited by 79 publications
(71 citation statements)
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“…No COVID-19 patient was documented among those without risk factors for COVID-19 acquisition. This nding is different from the epidemiologic reports from other countries where the outbreak situation of SARS-CoV-2 is ongoing [14]. The very low prevalence of COVID-19 among patients without risk factors for disease acquisition is also good supporting evidence for effective control of disease outbreak in Thailand.…”
Section: Discussioncontrasting
confidence: 70%
“…No COVID-19 patient was documented among those without risk factors for COVID-19 acquisition. This nding is different from the epidemiologic reports from other countries where the outbreak situation of SARS-CoV-2 is ongoing [14]. The very low prevalence of COVID-19 among patients without risk factors for disease acquisition is also good supporting evidence for effective control of disease outbreak in Thailand.…”
Section: Discussioncontrasting
confidence: 70%
“…It is notable, however, that 44% of COVID-19 negative patients reported fevers and systemic symptoms were common. In contrast to other reports, [15][16][17][18][20][21][22][23] Further investigation of co-infections in COVID-19 positive patients, and assessment of their potential impact on disease severity and outcomes is needed, especially if SARS-CoV-2 circulation extends to overlap with other highly prevalent seasonal respiratory pathogens.…”
Section: Hospitalization Treatment and Outcomesmentioning
confidence: 92%
“…Individuals have been shown to be infectious up to 2.5 days before symptom onset,20 and as many as 50% of infections seem to occur from presymptomatic individuals 21. Community prevalence of covid-19 in many countries is likely to be high 22. Modelling studies suggest that even a small reduction in community transmission could make a major difference to demand elsewhere in the system (eg, for hospital bed space and ventilators) 23…”
Section: Contested Interpretationsmentioning
confidence: 99%