Community Pharmacists‘ Attitudes Towards Clinical Utility and Ethical Implications of Pharmacogenetic Testing

Tuteja, Sony; Haynes, Kevin; Zayac, Cara; Sprague, Jon E.; Bernhardt, Barbara A.; Pyeritz, Reed E.

doi:10.2217/pme.13.85

Cited by 72 publications

(96 citation statements)

References 20 publications

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“…25 Three surveys were qualitative, that used one or combination of semi structure questionnaire, one-day meeting and case scenarios, 9,22,26 and with regard to design, four research were cohort study, 19,21,24,26 while the rest nine were Crosssectional studies, 9,12,15,16,18,[22][23][24][25] Pharmacogenetics or PG or pharmacogenetic testing and pharmacists or pharmacy students were discussed in all the articles. Table 1 presented the summary of included researches in this systematic review.…”

Section: Resultsmentioning

confidence: 99%

“…Seven studies have had a response rate of less than 60% for pharmacists, 12,15,16,18,19,23 while the remaining six have response rate more than 60%, 9,17,21,22,25 Only three researches used statistical analysis in questionnaire validation; 12,18,21 two studies used pilot study to validate the questionnaire in the studies; 17,19 majority of studies used experts reviews or kept silence on validity of questionnaire. 9,15,16,[22][23][24][25][26] In total 4,624 pharmacists participated in the reviewed articles.…”

Section: Resultsmentioning

confidence: 99%

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Knowledge, Attitude and Practice Concerning Pharmacogenomics among Pharmacists: A Systematic Review

Yau¹,

Aziz²,

Haque³

2015

JYP

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Background: Pharmacists are furnished with expert drug knowledge and have been considered as valuable resource of drug information, therefore, are well positioned to play a leading role in the application of pharmacogenomics (PG) in to clinical practice. This might prevent Chemotherapy related adverse events and improve patient outcomes, despite the ethical, privacy concerns and potential implications of lifelong genetic-data. Methods: This review is to evaluate and digest the various studies on Knowledge, Attitudes and Practice concerning pharmacogenomics among pharmacists and to suggest future research areas. 13 English published studies from 2004 to 2014 were selected. Studies involving Pharmacists of different area of practice and covering research from different continents were selected. Only studies on attitudes, knowledge and practice concerning pharmacogenetics among pharmacists from 2004 to 2014, and research articles published in English were selected. Non-research articles, studies done on general public; studies conducted among other healthcare professionals; studies on genetics of diseases or toxicogenetics were excluded. Results: Knowledge and practice regarding pharmacogenetics among pharmacists were poor despite good attitudes. There was knowledge advancement from 38% in 2005 to more than 50% 2013 in some countries. Some barriers to adoption of pharmacogenomics into patient care and interventional recommendations were highlighted. Conclusion: there is an urgent call for additional training of Pharmacogenomics among pharmacists and to incorporate pharmacogenomics into curriculum of pharmacy schools. Pharmacists and future pharmacists should be trained on how to critically evaluate the use, efficacy, and safety of available pharmacogenetic testing.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Knowledge, Attitude and Practice Concerning Pharmacogenomics among Pharmacists: A Systematic Review

Yau¹,

Aziz²,

Haque³

2015

JYP

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“…24 But this is an ongoing effort because there are still pharmacists who have expressed their lack of confidence in this matter. 8,23,25,26 Pharmacogenomic education in PharmD programs has grown rapidly. In 2005, only 32 out of 41 (78%) pharmacy schools that answered a survey described that they have some components of pharmacogenomics in their curriculum.…”

Section: Discussionmentioning

confidence: 99%

An Effective Approach to Teaching Pharmacogenomics in the First Year of Pharmacy Curriculum

Gálvez-Peralta

Szklarz

Geldenhuys

et al. 2018

American Journal of Pharmaceutical Education

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Objective. To develop an effective method in teaching pharmacogenomics as a part of a new course, Biopharmaceutics and Pharmacogenomics. Methods. Teaching effectiveness was measured by quizzes, retrospective pre-and post-surveys, team activities, and journal reflections. Four team activities were included in the course: genomic disease, patient case, genetic counselor and a debate about personalized medicine. Outcomes and course impact were evaluated at the end of the course. The evaluation methods included the assessment of knowledge, students' perceptions regarding the utility of team activities, the impact of the course on students' confidence to discuss pharmacogenomics with health care providers or patients, and long-term knowledge retention, measured in the following P2 semester. Results. Seventy-six students were enrolled in the course. Multiple assessments during the course demonstrated that students' knowledge of pharmacogenomics improved. The team activities had a positive impact on student learning, and the course improved their confidence level to discuss pharmacogenomics with another health care provider or a patient. While 86% of the students considered themselves "unconfident," "somewhat unconfident" or "neither confident nor unconfident" at the beginning of the course, 91% reported being "confident" or "somewhat confident" by the end of the course. This increase in confidence was statistically significant. Furthermore, students showed knowledge retention six months after taking the course. Conclusion. Implementation of a new course in pharmacogenomics was effective and well received by the students. It also prepared students for system-based therapeutics courses later in the curriculum.

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“…Another previous study in USA in 580 community pharmacists showed that around 87% community pharmacists had positive attitude toward pharmacogenetic test and around 57% realized their role in giving counseling to the patients about pharmacogenetic [11]. Moreover, in Qatar, the study about awareness and attitude towards pharmacogenetic was conducted among the pharmacists and doctors.…”

Section: Introductionmentioning

confidence: 99%

“…We used the questionnaire about knowledge, awareness and attitude of pharmacists towards pharmacogenetic from the previous study [11,13]. We translated the questionnaire into Bahasa Indonesia version at the Center of Language Practices Universitas Ahmad Dahlan.…”

Section: Introductionmentioning

confidence: 99%

Knowledge, Awareness and Attitude of Pharmacists toward Pharmacogenetic Practice: Perspective of Community and Hospital in Yogyakarta, Indonesia

Perwitasari¹,

Sl²,

Bp³

et al. 2017

J Community Med Health Educ

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Objectives: This study is aimed; to assess the knowledge, awareness and attitude of pharmacists in the community and hospital settings towards pharmacogenetic, to understand the differences of knowledge, awareness and attitude between community and hospital settings and to understand the factors predict the knowledge, awareness and attitude of the pharmacists. Methods:We conducted a cross-sectional study over 60 community pharmacies and 11 clinics and hospital pharmacies. We recruited 84 hospital pharmacists in the private hospitals and 24 community pharmacists. The questionnaire about knowledge, awareness and attitude of pharmacists towards pharmacogenetic were adopted from previous study. We also collected the data of demographic by interviewing the respondents. Results:Our study finds the significant differences of attitude between community and hospital pharmacists. The scores of knowledge, awareness and attitude in community setting are higher than the score of those in hospital settings. In the hospital setting, only education and CPD which may predict the awareness of pharmacists. In the community setting, characteristics which may predict the knowledge, awareness and attitude are outpatient services, work duration and CPD, respectively (p<0.05). Conclusion:The knowledge and awareness of pharmacists toward pharmacogenetic in Yogyakarta are good. Pharmacists' characteristics that may predict the knowledge, awareness and attitude toward pharmacogenetic are education, internal CPD, work duration, and types of patient's service.

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Community Pharmacists‘ Attitudes Towards Clinical Utility and Ethical Implications of Pharmacogenetic Testing

Cited by 72 publications

References 20 publications

Knowledge, Attitude and Practice Concerning Pharmacogenomics among Pharmacists: A Systematic Review

Knowledge, Attitude and Practice Concerning Pharmacogenomics among Pharmacists: A Systematic Review

An Effective Approach to Teaching Pharmacogenomics in the First Year of Pharmacy Curriculum

Knowledge, Awareness and Attitude of Pharmacists toward Pharmacogenetic Practice: Perspective of Community and Hospital in Yogyakarta, Indonesia

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