Community control of scabies: a model based on use of permethrin cream

Taplin, David; Meinking, Terri L.; Porcelain, Sherri L.; Athey, R.L.; Chen, J.A.; Castillero, Pedro M.; Sanchez, R.

doi:10.1016/0140-6736(91)92669-s

Cited by 157 publications

(110 citation statements)

References 11 publications

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“…In addition, community treatment of scabies by mass application of permethrin to all families of prisoners irrespective of symptoms is suggested. As reported in the literature, this approach to scabies control was effective and demonstrated excellent control rates [17].…”

Section: Discussionmentioning

confidence: 56%

Frequency of Scabies in Iraq: Survey in a Dermatology Clinic

Alsamarai

2009

J Infect Dev Ctries

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Background: The burden of scabies is highest in tropical countries, but recent data from Iraq are scanty. Objective: To estimate the frequency of scabies in patients of a dermatology clinic in central Iraq. Methodology: The study was conducted in Tikrit (Iraq), between May 2007 and February 2008. A total of 1,194 patients presenting to a dermatology clinic were included in the study. Results: During the study period, 132 [1.1%] patients with scabies were identified. The frequency was 13.5% in males and 8.6% in females [P = 0.007]. Frequency in children was 15.6% and 9.8% in adults [P = 0.007]. About 91% of cases were younger than 45 years. The treatment of scabies cases with 5% permethrin cream resulted in a cure rate of 80.3% following a single application, and was increased to 95.5% after a second application. Cure was achieved in all cases after a third application. Conclusion: Prevalence of scabies was high in a dermatology clinic, and prisoners were identified as high-risk group. Mass treatment of scabies either by oral ivermectin or topical permethrin is suggested.

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Section: Discussionmentioning

confidence: 56%

Frequency of Scabies in Iraq: Survey in a Dermatology Clinic

Alsamarai

2009

J Infect Dev Ctries

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“…Permethrin is adulticidal and ovicidal against the scabies mite and is therefore highly effective after a single application [53, 54]. However, in practice the prescribed regimen often involves two applications.…”

Section: Treatmentmentioning

confidence: 99%

A Review of Scabies: An Infestation More than Skin Deep

2018

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Human scabies, a common infestation, has a worldwide distribution with a variable impact and presentation depending on the clinical situation. In developed, high-income settings, health institution and residential home outbreaks challenge health and social care services. In resource-poor settings, it is the downstream sequelae of staphylococcal and streptococcal bacteraemia, induced by scratching, which have a significant impact on the long-term health of communities. Over the past decade scabies has been recognised as a “neglected tropical disease” (NTD) by the World Health Organisation, has an accepted practical system of global diagnostic criteria and is being adopted into integrated programmes of mass drug administration for NTDs in field settings. This review seeks to summarise the recent advances in the understanding of scabies and highlight the advocacy and research headlines with their implication for diagnosis and management of outbreaks and individuals. In addition, it will indicate the priorities and questions that remain.

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“…In situations where scabies is endemic, empirical treatment is often more cost-effective than attempting laboratory-based diagnoses. Intervention programs in Panama, Brazil, the Solomon Islands, and remote northern Australian Aboriginal communities have resulted in dramatic reductions in the prevalence of scabies and skin sores (58,103,116). These programs involve either mass topical treatment of community members with 5% permethrin or administration of oral ivermectin, with different models adapted to local conditions.…”

Section: Treatmentmentioning

confidence: 99%

Problems in Diagnosing Scabies, a Global Disease in Human and Animal Populations

2007

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SUMMARY Scabies is a worldwide disease and a major public health problem in many developing countries, related primarily to poverty and overcrowding. In remote Aboriginal communities in northern Australia, prevalences of up to 50% among children have been described, despite the availability of effective chemotherapy. Sarcoptic mange is also an important veterinary disease engendering significant morbidity and mortality in wild, domestic, and farmed animals. Scabies is caused by the ectoparasitic mite Sarcoptes scabiei burrowing into the host epidermis. Clinical symptoms include intensely itchy lesions that often are a precursor to secondary bacterial pyoderma, septicemia, and, in humans, poststreptococcal glomerulonephritis. Although diagnosed scabies cases can be successfully treated, the rash of the primary infestation takes 4 to 6 weeks to develop, and thus, transmission to others often occurs prior to therapy. In humans, the symptoms of scabies infestations can mimic other dermatological skin diseases, and traditional tests to diagnose scabies are less than 50% accurate. To aid early identification of disease and thus treatment, a simple, cheap, sensitive, and specific test for routine diagnosis of active scabies is essential. Recent developments leading to the expression and purification of S. scabiei recombinant antigens have identified a number of molecules with diagnostic potential, and current studies include the investigation and assessment of the accuracy of these recombinant proteins in identifying antibodies in individuals with active scabies and in differentiating those with past exposure. Early identification of disease will enable selective treatment of those affected, reduce transmission and the requirement for mass treatment, limit the potential for escalating mite resistance, and provide another means of controlling scabies in populations in areas of endemicity.

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Community control of scabies: a model based on use of permethrin cream

Cited by 157 publications

References 11 publications

Frequency of Scabies in Iraq: Survey in a Dermatology Clinic

Frequency of Scabies in Iraq: Survey in a Dermatology Clinic

A Review of Scabies: An Infestation More than Skin Deep

Problems in Diagnosing Scabies, a Global Disease in Human and Animal Populations

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