Community acquired Pseudomonas pneumonia in an immune competent host

Gharabaghi, Mehrnaz Asadi; Abdollahi, Seyed Mojtaba Mir; Safavi, Enayat; Abtahi, Hamidreza

doi:10.1136/bcr.01.2012.5673

Cited by 13 publications

(9 citation statements)

References 8 publications

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“…Repeated sputum for gram stain and bacterial culture were sterile, sputum smears for Ziehl-Neelsen staining were negative for acid fast organisms, and sputum for fungal culture showed insignificant growth. We reviewed the literature for cavitatory lesions in immunodeficient individuals, and found that pneumonia is typically caused by Staphylococcus aureus [3] or Pseudomonas aeruginosa [4], and Mycobacterium tuberculosis [5–7] is rarely reported with Rhodococcus equi [8–10] and Nocardia asteroids [11–17]. …”

Section: Discussionmentioning

confidence: 99%

Allergic Broncho Pulmonary Aspergillosis Complicated by Nocardiosis

Sharma

Ghosh

Kamble

et al. 2012

Case Reports in Pulmonology

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We describe a 70-year-old male with a history of diabetes mellitus, hypertension, and asthma who presented with increasing breathlessness for 5 months. He was diagnosed to have allergic bronchopulmonary aspergillosis (ABPA) by serological and radiographic criteria. He was treated with steroids and itraconazole. After initial improvement, he developed fever with cough and mucopurulent sputum. X-ray chest revealed multiple cavities with air fluid level. Patient was treated with antibiotics without any response. Sputum was negative for acid fast bacilli (AFB). Sputum culture for bacteria and fungus did not reveal any significant growth; however a delayed growth of Nocardia was noted on fungal plates. Modified Ziehl Nelsen stain was positive for AFB. Patient was treated with cotrimoxazole. We discuss the serological and radiological criteria of ABPA, presentation and treatment of nocardia pulmonary infection and other possible causes of necrotizing pneumonia in immunocompromised settings.

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Section: Discussionmentioning

confidence: 99%

Allergic Broncho Pulmonary Aspergillosis Complicated by Nocardiosis

Sharma

Ghosh

Kamble

et al. 2012

Case Reports in Pulmonology

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“…Pseudomonas aeruginosa is a common nosocomial pathogen that often causes pneumonia in hospitalized patients [1,2] , most of whom have underlying medical conditions or risk factors for Pseudomonas infection. Although rare, case reports and reviews have described healthy individuals who have developed community-acquired pneumonia (CAP) caused by P. aeruginosa [3–8] that is often rapidly progressive and fatal.…”

Section: Introductionmentioning

confidence: 99%

Community-acquired, hospital-acquired, and healthcare-associated pneumonia caused by Pseudomonas aeruginosa

Fujii

Seki

Higashiguchi

et al. 2014

Respiratory Medicine Case Reports

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We describe three types of Pseudomonas aeruginosa pneumonia.Case 1. P. aeruginosa was isolated from the blood and sputum of a 29-year-old male non-smoker who developed severe community-acquired pneumonia (CAP). Piperacillin was initially effective, but fever and lobular pneumonia with cavities developed seven days after discharge. Intravenous piperacillin/tazobactam and tobramycin were administered for four weeks, followed by oral ciprofloxacin for two weeks. He finally recovered, but developed recurrent CAP due to P. aeruginosa despite appropriate antibiotic therapy and immunocompetent status.Case 2. P. aeruginosa was isolated from the blood and sputum of a 57-year-old woman with renal cancer who developed hospital-acquired pneumonia (HAP) after surgical treatment. She recovered after meropenem administration for four weeks.Case 3. A 67-year-old woman with systemic sclerosis and malignant lymphoma who was followed up on an outpatient basis underwent immunosuppressive therapy. Thereafter, she developed pneumonia and was admitted to our institution where P aeruginosa was isolated from blood and sputum samples. Healthcare-associated pneumonia (HCAP) was diagnosed and effectively treated with tobramycin and ciprofloxacin.P. aeruginosa is not only a causative pathogen of HAP and HCAP, but possibly also of CAP.

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“…In the literature, we found 13 cases of necrotizing CAP due to P. aeruginosa associated with cavitation. Table 1 summarizes the 11 most recent cases [[1], [2], [3], [4], [5], [6], [7], [8], [9], [10]]. The main risk factors for necrotizing CAP due to P. aeruginosa are: lung structural abnormalities (including cystic fibrosis, emphysema, bronchial dilatation, chronic obstructive pulmonary disease), immunocompromised condition (including neoplasia, neutropenia, prolonged antibacterial therapy, immunosuppression), and exposure to contaminated liquids (including hot tub, spa, humidifier) [1,2].…”

Section: Discussionmentioning

confidence: 99%

“…Regarding antimicrobial management for CAP, the literature is summarized in Table 1 [[1], [2], [3], [4], [5], [6], [7], [8], [9], [10]]. It is generally not appropriate to administer empiric anti-Pseudomonas therapy.…”

Section: Discussionmentioning

confidence: 99%

Septic shock secondary to an acute necrotizing community-acquired pneumonia with bacteremia due to Pseudomonas aeruginosa

Rivière¹,

Patin²,

Delaporte³

et al. 2019

IDCases

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Highlights Necrotizing acute community-acquired pneumonia due to Pseudomonas aeruginosa are rare. Second description of a septic shock secondary to a necrotizing CAP with bacteremia due to P. aeruginosa for which pulmonary origin was proven by bronchoalveolar lavage fluid on a patient who survived. Anti-pseudomonal monotherapy may be may be a better option for older patients Despite risk factors related to the host or to the bacteria, the evolution remains unpredictable.

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Community acquired Pseudomonas pneumonia in an immune competent host

Cited by 13 publications

References 8 publications

Allergic Broncho Pulmonary Aspergillosis Complicated by Nocardiosis

Allergic Broncho Pulmonary Aspergillosis Complicated by Nocardiosis

Community-acquired, hospital-acquired, and healthcare-associated pneumonia caused by Pseudomonas aeruginosa

Septic shock secondary to an acute necrotizing community-acquired pneumonia with bacteremia due to Pseudomonas aeruginosa

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