Community-acquired pseudomonas aeruginosa liver abscess with portal vein thrombosis in a child

Abstract

Pseudomonas aeruginosa is usually considered a relatively rare pathogen of pyogenic liver abscess in healthy children. A 3-year-old girl presented with fever, abdominal pain, and vomiting. Ultrasonography of the abdomen showed multiple liver abscesses. During her stay in hospital, she developed portal vein thrombosis, hepatic encephalopathy, and multiorgan dysfunction. Her blood culture and pus culture grew pseudomonas aeruginosa. She was started on intravenous antibiotics and supportive treatment. Ultrasound guided aspiration was done and a pigtail catheter was inserted. However, she did not respond to the treatment and died on the 14th day of admission. The immune work up of the patient was normal. Through this case, we wish to highlight this unusual case of community-acquired pseudomonas aeruginosa liver abscess in a previously healthy child. Clinicians should be aware of this association for early diagnosis and timely management.

Assessment of Risk Factors in Pyogenic Liver Abscesses in Children

“…In children, only raised GGT and open surgical procedures were associated with poor outcomes. [ 11 23 ] In this study, elevated baseline GGT (>350 IU/L), clinical icterus, culture positivity and high-risk characters as rupture/impending rupture were only statistically significant indicators of morbidity (duration of defervescence, the P = 0.05,0.04, 0.04 and 0.01, respectively).…”