Community-acquired Methicillin-resistant Staphylococcus aureus among Military Recruits

Abstract

We report an outbreak of 235 community-acquired methicillin-resistant Staphylococcus aureus (MRSA) infections among military recruits. In this unique environment, the close contact between recruits and the physical demands of training may have contributed to the spread of MRSA. Control measures included improved hygiene and aggressive clinical treatment.

Safety and immunogenicity of a recombinant Staphylococcus aureus α-toxoid and a recombinant Panton-Valentine leukocidin subunit, in healthy adults

“…p-values were calculated using a Wald test statistic for group in a generalized linear model for count outcomes. 3 SAEs were malignant astrocytoma (probably unrelated), hospitalization for non-cardiac chest pain (probably unrelated), hospitalization for alcoholism relapse (probably unrelated), hospitalization for pneumonia (probably unrelated), and thrombocytopenia secondary to idiopathic thrombocytopenic purpura (unknown relationship).…”

“…Outbreaks of community acquired skin and soft-tissue infections (SSTIs) due to methicillin-resistant S. aureus have been observed in prisoners, athletes, military personnel, and other risk groups. [1][2][3][4][5] S. aureus SSTIs have become a significant public health issue for the US military over the last decade, affecting service members during training and overseas deployment. 4,[6][7][8] Cumulative SSTI rates during training range between 4-6%, 4,9,10 and SSTIs were estimated to be the cause of 41,951 ambulatory visits and 1,054 hospital admissions for active duty military members in 2014.…”

Characterization of a Strain of Community-AssociatedMethicillin-Resistant Staphylococcus aureus WidelyDisseminated in the UnitedStates

“…An isolate of the same lineage as USA400 (also known as S. aureus MW-2) was responsible for a series of infections in health care settings across Canada (61), infections in Native Americans (31) and among children in day care (33), and an outbreak of S. aureus infection on a maternity ward of a hospital in New York (62). USA300 isolates have been recovered from a variety of community populations, including children (5,39), correctional facility inmates (7,10), participants in sports teams (9,40), men who have sex with men (8,34,42), and military recruits (72). Over the last 3 years, outbreak investigations conducted by the Centers for Disease Control and Prevention (CDC) in diverse geographic locations and with diverse patient populations often yielded the same USA300 PFGE pattern, designated USA300-0114, from wound cultures and other clinical specimens (40).…”

Type IV SCCmec found in decade old Brazilian MRSA isolates

“…Until recently, infection with MRSA was an event almost exclusively restricted to hospitalised patients, with most nosocomial MRSA strains bearing one of three types of SCCmec, either type I, II or III [3]. However, MRSA community infections have been reported with increasing frequency [4][5][6]. These infections, which are clinically similar to the ones caused by methicillin susceptible S. aureus (MSSA), usually affect individuals who do not bear the risk factors for the acquisition of MRSA [7].…”