Community-acquired infection to Raoultella ornithinolytica presenting as appendicitis and shock in a healthy individual

Hajjar, Roy; Schwenter, Frank; Su, S.; Gasse, Marie-Christine; Sebajang, Herawaty

doi:10.1093/jscr/rjy097

Cited by 11 publications

(10 citation statements)

References 11 publications

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“…The pathogenicity of R. ornithinolytica is uncertain but it has been associated with fish and causes scombroid syndrome [ 37 ]. The symptoms of which includes vomiting and flushing [ 38 ]. S. marcescens has been isolated from cooked refrigerated pork meat and can cause pneumonia and urinary tract infection [ 39 , 40 ].…”

Section: Discussionmentioning

confidence: 99%

Microbiological quality of kitchens sponges used in university student dormitories

et al. 2020

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Background Kitchen sponges are a major source of cross-contamination as they can transfer foodborne pathogens, infectious agents and spoilage causing microorganisms to food contact surfaces. Several studies have revealed that university students adopt poor practices regarding food safety, hygiene, and the handling of kitchen cleaning equipment. Methods A total of fifty kitchen sponges were collected along with a questionnaire addressing social demographics and kitchen sponge usage by students living at the University of Sharjah dormitories. The effect of storage (3 and 10 days) on the microbial population of kitchen sponges at room temperature (21 °C) was assessed. Enterobacteriaceae isolated from sponges were identified and their antibiotic resistance determined. Results Student responses revealed that kitchen sponges used to clean food contact surfaces were also used to clean the oven (32%), sink (26%), refrigerator (10%), and to clean spills on the floor (4%). Kitchen sponges contained high counts of mesophilic aerobic bacteria (7.9 log 10 /cm 3 ) , coliform (7.2 log 10 /cm 3 ), Enterobacteriaceae (7.3 log 10 /cm 3 ) and yeasts and molds (7.0 log 10 /cm 3 ). After storage of the sponges at room temperature (21 °C) for 3 and 10 days, the number of mesophilic aerobic bacteria, coliform, Enterobacteriaceae and yeasts and molds decreased by 0.4 and 1.3 log 10 /cm 3 , 0.7 and 1.4 log 10 /cm 3 , 0.4 and 1.1 log 10 /cm 3 , and 0.6 and 1.3 log 10 /cm 3 , respectively. The most frequently isolated Enterobacteriaceae were Enterobacter cloacae (56%) and Klebsiella oxytoca (16%) . All E. cloacae isolates were resistant to amoxicillin, cefalotin, cefoxitin and cefuroxime axetil. Conclusions This study showed that students living in dormitories lacked good hygienic practices and were at increased risk of food poisoning. Kitchen sponges were highly contaminated with potentially pathogenic bacteria which could be transferred from the general kitchen environment to food contact surfaces and consequently lead to food contamination.

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Section: Discussionmentioning

confidence: 99%

Microbiological quality of kitchens sponges used in university student dormitories

et al. 2020

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“…1,27 This technology was used in our previous work to properly identify R. ornithinolytica in a patient with gut-derived sepsis. 28 However, because mass spectra from R. ornithinolytica and R. planticola are highly similar, difficulty in differentiating between these two species has been reported with MALDI-TOF technology. 29,30 Misidentification as Enterobacter aerogenes (now Klebsiella aerogenes) has also been reported with the use of MALDI-TOF.…”

Section: Identificationmentioning

confidence: 99%

“…Nonetheless, rare cases involving healthy patients with no identifiable risk factors exist, and usually present as food poisoning and acute gastroenteritis. 12,28 Urological Infections Cases of urinary tract infection (UTI) with R. ornithinolytica are very scarce. Table 2 summarizes the previously detailed cases of UTIs with this pathogen.…”

Section: Gastrointestinal and Hepatobiliary Infectionsmentioning

confidence: 99%

<p><em>Raoultella ornithinolytica</em>: Emergence and Resistance</p>

Hajjar¹,

Ambaraghassi²,

Sebajang³

et al. 2020

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Raoultella ornithinolytica is an encapsulated Gram-negative, oxidase-negative, catalase-positive, aerobic, non-motile rod that belongs to the Enterobacteriaceae family. This bacterium was initially classified in the genus Klebsiella as Klebsiella ornithinolytica, until the creation of the genus Raoultella in 2001. R. ornithinolytica is usually found in water environments and soil, and due to its ability to convert histidine to histamine, it has been associated with histamine poisoning in humans. R. ornithinolytica is an emerging entity in human infections, with several reports of virulent infections in comorbid at-risk patients. Increasing reports are potentially due to better and more precise identification tools. The objective of this article is to provide a comprehensive review of reported cases of R. ornithinolytica infections, the emergent virulence of described multiresistant strains, and an overview of currently used identification methods.

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“…Raoultella ornithinolytica is closely related to Klebsiella and belongs to Enterobacteriaceae family (Beye et al, 2018; Hajjar et al, 2018). R. ornithinolytica is usually found in animals, soil, and botanical environment.…”

Section: Introductionmentioning

confidence: 99%

Emergence of Colistin Resistance Gene mcr-8 and Its Variant in Raoultella ornithinolytica

Wang

Zhou

et al. 2019

Front. Microbiol.

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Recently, a novel mobile colistin resistance gene, mcr-8 , was identified in Klebsiella pneumoniae . Here, we report the identification of mcr-8 and its variant, mcr-8.4 , in Raoultella ornithinolytica isolates which also belong to Enterobacteriaceae family. The mcr-8 gene was located on transferrable plasmids with difference sizes. Notably, the transferability of mcr-8 -carrying plasmids was enhanced once they entered into Escherichia coli hosts and multiple β-lactamase genes could co-transfer with mcr-8 . These findings expand our knowledge of mcr-8 -carrying bacterial species.

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Community-acquired infection to Raoultella ornithinolytica presenting as appendicitis and shock in a healthy individual

Cited by 11 publications

References 11 publications

Microbiological quality of kitchens sponges used in university student dormitories

Microbiological quality of kitchens sponges used in university student dormitories

<p><em>Raoultella ornithinolytica</em>: Emergence and Resistance</p>

Emergence of Colistin Resistance Gene mcr-8 and Its Variant in Raoultella ornithinolytica

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