1992
DOI: 10.1016/0378-8741(92)90015-j
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Commonly used Indian abortifacient plants with special reference to their teratologic effects in rats

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Cited by 111 publications
(49 citation statements)
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“…In this respect, the historical saga of thalidomide, a sedative used in the treatment of hyperemesis gravidarum, but later found to be responsible for a string of birth defects readily comes to mind [10][11][12][13]. Many herbal remedies have been reported to impair fetal development following usage in pregnancy [14][15][16][17][18][19][20][21][22].…”
Section: Introductionmentioning
confidence: 99%
“…In this respect, the historical saga of thalidomide, a sedative used in the treatment of hyperemesis gravidarum, but later found to be responsible for a string of birth defects readily comes to mind [10][11][12][13]. Many herbal remedies have been reported to impair fetal development following usage in pregnancy [14][15][16][17][18][19][20][21][22].…”
Section: Introductionmentioning
confidence: 99%
“…The predominant thyroidal hormone in circulation is T4, while T3 is mostly generated from T4 in peripheral tissues by outer ring monodeiodination [10,11]. Since only T4, and not T3, was enhanced by EKE, it appears that EKE might be stimulating the synthesis and/or release of T4 directly at the glandular level, and not through the peripheral conversion of T4 to T3.…”
Section: Discussionmentioning
confidence: 99%
“…Bioactivity of seed extract as an antifertility agent was reported by pharmacologists in 1970s. Decoction or hot water extract of dried seeds was administered orally as an antifertility and abortifacient agent to prevent conception [5][6][7][8][9][10][11] .…”
Section: Introductionmentioning
confidence: 99%