Commonly Used Imaging Techniques for Diagnosis and Staging

Barentsz, Jelle O.; Takahashi, Satoru; Oyen, Wim J.G.; Mus, Roel; Mulder, Pieter De; Reznek, Rodney H.; Oudkerk, Matthijs; Mali, Wim

doi:10.1200/jco.2006.06.5946

Cited by 81 publications

(60 citation statements)

References 22 publications

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“…On the other hand, CT of the thorax is not generally recommended because of its very low yield (5). Although widely available and affordable, these techniques have important limitations (6). Chest radiography is insensitive in detecting mediastinal and hilar lymphadenopathies because of structure overlapping and inadequate soft-tissue contrast.…”

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confidence: 99%

18F-FDG PET Can Replace Conventional Work-up in Primary M Staging of Nonkeratinizing Nasopharyngeal Carcinoma

Liu¹,

Lin²,

Chang³

et al. 2007

Journal of Nuclear Medicine

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Conventional work-up (CWU) with chest radiography, abdominal ultrasonography, and skeletal scintigraphy has limited value in M staging of nonkeratinizing nasopharyngeal carcinoma (NPC). Our aim was to evaluate whether 18 F-FDG PET could replace CWU by comparing their diagnostic efficacies. Methods: Patients with histologically proven nonkeratinizing NPC and no prior treatment were prospectively enrolled. All study participants underwent CWU and 18 F-FDG PET for primary M staging. Distant metastasis was considered to be present if there was any reliable evidence identified within 1 y after diagnosis. The comparative diagnostic efficacies of 18 F-FDG PET, CWU, and the combination of 18 F-FDG PET and CWU (PET1CWU) were evaluated using the areas under the receiver-operating-characteristic (ROC) curves. Results: Sixty-one (20.3%) of 300 eligible patients were found to have distant metastases. On a patient-based analysis, 18 F-FDG PET was found to be more effective than CWU (P , 0.001), whereas it was equally effective with PET1CWU (P 5 0.130). On region-based analyses, 18 F-FDG PET was more effective than skeletal scintigraphy and chest radiography for detecting bone metastases (P , 0.001) and chest metastases (P , 0.001), respectively. 18 F-FDG PET and abdominal ultrasound were equally effective for detecting hepatic metastases (P 5 0.127). On region-based analyses, the combination of 18 F-FDG PET and CWU did not yield any noticeable increase in diagnostic efficacy. Conclusion: 18 F-FDG PET can replace CWU in primary M staging of nonkeratinizing NPC.

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confidence: 99%

18F-FDG PET Can Replace Conventional Work-up in Primary M Staging of Nonkeratinizing Nasopharyngeal Carcinoma

Liu¹,

Lin²,

Chang³

et al. 2007

Journal of Nuclear Medicine

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“…As imaging technology continues to evolve [9], the purpose of this study was to systematically review the current role of imaging in assessing LN status in gastric cancer. This study reviews the role of imaging in discriminating node-negative from node-positive patients, rather than its role in assessing nodal stage according to excluded.…”

Section: Introductionmentioning

confidence: 99%

Imaging in assessing lymph node status in gastric cancer

2009

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“…Computerized tomography (CT) of the chest, abdomen and pelvis are required as initial staging investigations with the mandatory application of oral and intravenous contrast media [5,6]. For the evaluation of the lung and mediastinum, chest CT scan is more sensitive than plain X-ray films [7,8].…”

Section: Nsgct Cs1: Definition and Stagingmentioning

confidence: 99%

Current Concepts in Management of Stage I NSGCT

Ahluwalia

Gautam

2016

Indian J Surg Oncol

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While about 50% of non-seminomatous germ cell tumors of the testes present as clinical stage I (CSI), further management of these patients continues to be mired in controversy. Active surveillance is a frontline option for low-risk CS I patients and according to some, even the high-risk ones with high embryonal carcinoma (ECA) component and vascular invasion (VI). However, it carries the disadvantage of long-term surveillance, the need for prolonged chemotherapy in case of recurrence and the possibility of secondary malignancies due to radiation exposure from frequent CT scans. One or two cycles of BEP chemotherapy is a popular alternative to active surveillance which carries a very low relapse rate, but valid concerns about overtreatment of a majority of patients, with the attendant chemotherapy-related toxicity exist. Retroperitoneal lymph node dissection has been used as a means of avoiding chemotherapy, especially in high-risk patients, but carries the disadvantage of a high surgical morbidity and complications. As with any major surgical procedure, the best results are dependent on the experience and skill of the individual surgeon.

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Commonly Used Imaging Techniques for Diagnosis and Staging

Cited by 81 publications

References 22 publications

18F-FDG PET Can Replace Conventional Work-up in Primary M Staging of Nonkeratinizing Nasopharyngeal Carcinoma

18F-FDG PET Can Replace Conventional Work-up in Primary M Staging of Nonkeratinizing Nasopharyngeal Carcinoma

Imaging in assessing lymph node status in gastric cancer

Current Concepts in Management of Stage I NSGCT

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