Monkeypox infection is characterized by rash developing 1-4 days after prodromal symptoms, as deep-seated, vesicular, or pustular. It begins centrally and spread to the limbs. The rash can last 2-4 weeks, progressing to macules, papules, vesicles, pustules, and eventually scabs and crusts. So, perform a visual inspection of the skin and oral, genital, and perianal areas in women with a new rash. Symptomatic individuals should be isolated, lesions should be covered, and wear masks as monkeypox is contagious.