Common variable immunodeficiency in association with autoimmune encephalitis, collagenous gastritis, and colitis

Collagenous gastritis presenting as chronic heartburn in a patient with psoriatic arthritis

“…[13][14][15][16] Several comorbid conditions have been concomitantly reported, such as common variable immunodeficiency, primary IgM deficiency, autoimmune disorders, and psoriatic arthropathy. 10,11,[17][18][19][20] Our patient had a history of psoriatic arthropathy and was on treatment with hydroxychloroquine for this. One prior case of collagenous colitis has been reported in a patient with psoriatic arthropathy, which was attributed to the patient's treatment with secukinumab.…”

“…8,10 Co-existing collagenous colitis has sometimes been reported. 6,[11][12][13] Although histopathologic features are quite characteristic, its exact pathophysiologic mechanism remains unknown. Use of certain medications such as olmesartan and non-steroidal anti-inflammatory drugs have often been associated with the development of chronic gastritis.…”