Common skin infections in children

Sladden, Michael J; Johnston, Graham A.R.

doi:10.1136/bmj.329.7457.95

Cited by 98 publications

(118 citation statements)

References 21 publications

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“…Impetigo is a contagious bacterial skin infection that affects both adults and children [1]. In general practice, it is considered the third most common dermatological condition diagnosed among children between the ages of 6 and 11 years [1].…”

Section: Introductionmentioning

confidence: 99%

Topical Retapamulin Ointment, 1%, versus Sodium Fusidate Ointment, 2%, for Impetigo: A Randomized, Observer-Blinded, Noninferiority Study

et al. 2007

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Background: Retapamulin is a novel pleuromutilin antibacterial developed for topical use. Objective: To compare the efficacy and safety of retapamulin ointment, 1% (twice daily for 5 days), with sodium fusidate ointment, 2% (3 times daily for 7 days), in impetigo. Methods: A randomized (2:1 retapamulin to sodium fusidate), observer-blinded, noninferiority, phase III study in 519 adult and pediatric (aged ≧9 months) subjects. Results: Retapamulin and sodium fusidate had comparable clinical efficacies (per-protocol population: 99.1 and 94.0%, respectively; difference: 5.1%, 95% confidence interval: 1.1–9.0%, p = 0.003; intent-to-treat population: 94.8 and 90.1%, respectively; difference: 4.7%, 95% confidence interval: –0.4 to 9.7%, p = 0.062). Bacteriological efficacies were similar. Success rates in the small numbers of sodium-fusidate-, methicillin- and mupirocin-resistant Staphylococcus aureus were good for retapamulin (9/9, 8/8 and 6/6, respectively). Both drugs were well tolerated. Conclusion: Retapamulin is a highly effective and convenient new treatment option for impetigo, with efficacy against isolates resistant to existing therapies.

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Section: Introductionmentioning

confidence: 99%

Topical Retapamulin Ointment, 1%, versus Sodium Fusidate Ointment, 2%, for Impetigo: A Randomized, Observer-Blinded, Noninferiority Study

et al. 2007

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“…Yüzeyel epidermisin oldukça bulaşıcı bir infeksiyonu olup sıklıkla 2-5 yaş arasındaki çocukları etkiler. Tedavisiz bırakıldığında dahi sıklıkla skarsız olarak iyileşen impetigoya en sık yol açan bakteri S.Aureus'tur, A grubu β-hemolitik streptokoklar ikinci sırada yer alır 3,4 . İmpetigonun non-büllöz ve büllöz olmak üzere iki tipi mevcuttur.…”

Section: İmpetigounclassified

“…Tanı sıklıkla klinik olarak konur, gram boyama veya kültür ile doğrulanabilir. Kültür özellikle metisiline dirençli S.Aureus (MRSA) şüphesi bulunduğunda anlamlı olabilir 3,4 . Non-büllöz impetigo, hızla küçük bir veziküle dönüşen eritematöz makül veya papül ile başlar.…”

Section: İmpetigounclassified

Common Bacterial Skin Infections in Children

Yaylı¹

2011

Turkderm

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ÖzetBakteriyel deri infeksiyonları, çocukluk çağında hastane başvurularının başlıca sebeplerindendir. Hafif şiddette yüzeyel folikülitlerden, hastane yatışı gerektiren stafilokoksik haşlamış deri sendromu gibi komplike infeksiyonlara kadar geniş bir grup hastalığı içerir. Bu infeksiyonlara en sık neden olan patojenler stafilokok ve streptokoklardır. Bakterilerin genel olarak antimikrobiyal direncindeki artış, deri infeksiyonlarının tedavisini zorlaştırmaktadır. Bu nedenle, klinik görünümüyle hafif şiddette olarak değerlendirilen infeksiyonların tedavisi bile önem taşımaktadır. Sum maryBacterial skin infections are among the major reasons for visits to outpatient clinics in childhood period. They contain a large group diseases from mild superficial folliculitis to complicated infections requiring hospitalization, such as staphylococcal scalded skin syndrome. The main pathogens that involved in these infections are staphylococcus and streptococci. The overall increase in antimicrobial resistance of bacteria makes it difficult to treat skin infections. Therefore, it is crucial even treatment of the infections considered as mild infection according to the clinical apearance. Gi riflDermatoloji ve pediatri polikliniklerinde en sık görülen hastalık gruplarından birisi de bakteriyel deri infeksiyonlarıdır. Bakteriyel mikroorganizmalar; impetigo, folikülit, fronkül gibi görece hafif tablolardan, tanısal zorluklar yaratabilen şiddetli deri infeksiyonlarına kadar çok çeşitli hastalıklar oluşturur. Deri infeksiyonlarına en sık yol açan bakteriler sırasıyla Stafilokokkus aureus ve A grubu β-hemolitik streptokoklardır 1 . Bu makalede çocuklarda sık görülen bakteriyel deri infeksiyonları (Tablo 1), tedavi seçenekleri (Tablo 2) ile birlikte gözden geçirilecektir.

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“…2 Although most warts resolve within two years, some persist and become large and painful. 5 Painful warts must be treated. A technique that does not cause scarring should be used; scars on the soles of the feet may be painful for years.…”

Section: Introductionmentioning

confidence: 99%

Comparative study between cryotherapy and salicylic acid in the treatment of plantar warts in Erbil - Iraq

Muhamad¹,

Sulaiman²

2018

ZJMS

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Abstract* Rizgary Teaching Hospital, Erbil, Iraq. IntroductionPlantar warts, also known as verruca plantaris, are benign epithelial tumors, caused by the human papillomavirus (HPV) occurring on the soler toes of the feet. On the soles, these are often painful from pressure when walking, due to their deep inward growth. Plantar warts are common in older children and young adults, accounting for 30% of cutaneous warts. Plantar warts are caused by HPV-1, 2, 4, 27 or 57. [1][2][3][4] HPVs form a large group of closely related viruses, distinguished one from another on the basis of their DNA. To date, about 100 types have been recognized and characterized. All papillomavirus types have a tropism for stratified squamous epithelial cells, but they vary in their specificity for different anatomical sites. Papillomaviruses are small 50 to 55-nm-diameter DNA viruses that infect squamous epithelia, causing cell proliferation. The commonest effect of HPV infection is the development of warts (verrucae).2 A plantar wart at first appears as a small shining 'sago-grain 'papule, but soon assumes the typical appearance of a sharply defined, rounded lesion, with a rough, keratotic surface surrounded by a smooth collar of a thickened horn. Individuals may be affected by a single or numerous lesions.2 The soft, pulpy cores are surrounded by a firm, horny ring. Over the surface of the plantar wart, most clearly if the top is shaved off, multiple small black points may be seen that represent dilated capillary loops within elongated dermal papillae.1 Pain is a common but variable symptom. It may be severe and disabling, but may be absent, and many warts are discovered only on routine inspection. 2Background and objective: Plantar warts are hard, grainy growths that usually appear on the heels or balls of feet. Plantar warts are caused by the human papillomavirus, usually self-limiting, but treatment is generally recommended to lessen symptoms, decrease duration, and reduce transmission. The study aimed to evaluate the clinical effectiveness of topical 40% salicylic acid in comparison to cryotherapy in the treatment of plantar wart. Methods: This study was conducted from March 2015 to January 2016 on 70 patients with plantar wart who attended the consultation clinic of dermatology department in Rizgary teaching hospital. Patients were randomly allocated to two groups: cryotherapy treatment with liquid nitrogen every two or three weeks and self-application of salicylic acid daily. Results: Sixty patients aged 12 to 60 years were included in the analysis at 13 weeks. Cure rates were 66.7% in the cryotherapy group and 80% in the salicylic acid group. A significant association was found between the duration of wart before treatment and cure rates (P <0.001). Conclusion:No difference in effectiveness between cryotherapy and topical salicylic acid 40% in the treatment of plantar warts was found.

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Common skin infections in children

Cited by 98 publications

References 21 publications

Topical Retapamulin Ointment, 1%, versus Sodium Fusidate Ointment, 2%, for Impetigo: A Randomized, Observer-Blinded, Noninferiority Study

Topical Retapamulin Ointment, 1%, versus Sodium Fusidate Ointment, 2%, for Impetigo: A Randomized, Observer-Blinded, Noninferiority Study

Common Bacterial Skin Infections in Children

Comparative study between cryotherapy and salicylic acid in the treatment of plantar warts in Erbil - Iraq

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