2011
DOI: 10.4061/2011/236239
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Common Secondary Causes of Resistant Hypertension and Rational for Treatment

Abstract: Resistant hypertension is defined as uncontrolled blood pressure despite the use of three antihypertensive drugs, including a diuretic, in optimal doses. Treatment resistance can be attributed to poor adherence to antihypertensive drugs, excessive salt intake, physician inertia, inappropriate or inadequate medication, and secondary hypertension. Drug-induced hypertension, obstructive sleep apnoea, primary aldosteronism, and chronic kidney disease represent the most common secondary causes of resistant hyperten… Show more

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Cited by 76 publications
(59 citation statements)
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References 206 publications
(167 reference statements)
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“…Sabe-se que o uso de glicocorticoides em longo prazo está associado a uma alta prevalência de hipertensão arterial (32) e hiperglicemia (33) , assim como o uso de anti-inflamatórios não esteroidais (AINES) pode exarcebar a pré-existência da hipertensão (34) . A combinação desses dados descritos é capaz de influenciar na QV desses pacientes.…”
Section: Discussionunclassified
“…Sabe-se que o uso de glicocorticoides em longo prazo está associado a uma alta prevalência de hipertensão arterial (32) e hiperglicemia (33) , assim como o uso de anti-inflamatórios não esteroidais (AINES) pode exarcebar a pré-existência da hipertensão (34) . A combinação desses dados descritos é capaz de influenciar na QV desses pacientes.…”
Section: Discussionunclassified
“…Belli aralıklarla ventrikül fonksiyonlarının değerlendirilmesi ve pulmoner arter basıncının ölçülmesi açısından ekokardiyografi yapılması önerilmektedir (37). OUAS ve hipertansiyonu olan hastaların tedavisinde tek başına CPAP'nin etkin olmadığı, tedaviye etyopatogenezde rol oynayan renin aldosteron sistemini bloke eden ilaçların da eklenmesi gerektiği vurgulanmıştır (42).…”
Section: Hipertansiyonunclassified
“…The pathogenesis of hypertension in patients with obstructive sleep apnoea (OSA) seems to be multifactorial. Possible explanations involve increased tension of the sympathetic nervous system, leading to elevated blood pressure (BP) as a result of higher cardiac output and vascular resistance and fluid retention secondary to tissue hypoxia and the effects of an increased aldosterone level [20]. Interesting results were obtained by Gonzaga et al, who investigated the prevalence of primary aldosteronism and obstructive sleep apnoea in patients with resistant hypertension.…”
Section: Obstructive Sleep Apneamentioning
confidence: 99%