Common Origin of the Innominate and Carotid Arteries: Prevalence, Nomenclature, and Surgical Implications

Katz, Jason C.; Chakravarti, Sujata; Ko, H. Helen; Lytrivi, Irene D.; Srivastava, Shubhika; Lai, Wyman W.; Parness, Ira A.; Nguyen, Khanh; Nielsen, James C.

doi:10.1016/j.echo.2006.06.018

Cited by 19 publications

(16 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A third explanation may implicate a genetic component. It is well documented that a deletion in chromosome 22q11 results in bovine arch in concordance with other structural heart defects such as VSD, ASD, and coarctation …”

Section: Discussionmentioning

confidence: 96%

“…The most common configuration occurs in approximately 80% of the population and consists of three separate origins for the BCA, LCCA, and LSA . A common origin of the BCA and LCCA (also known as bovine arch) is the second most common variation occurring in 6.7% to 20% of patients without TAA or dissection . The third most common is the left vertebral artery arising directly from the aortic arch in 4% to 6% of the general population .…”

Section: Discussionmentioning

confidence: 99%

“…6 A common origin of the BCA and LCCA (also known as bovine arch) is the second most common variation occurring in 6.7% to 20% of patients without TAA or dissection. 1,4,[6][7][8] The third most common is the left vertebral artery arising directly from the aortic arch in 4% to 6% of the general population. 7,9,10 The present study shows that thoracic aortic branching patterns, specifically the bovine arch are more common in patients with aortic dissection than in the general population.…”

Section: Discussionmentioning

confidence: 99%

“…It is well documented that a deletion in chromosome 22q11 results in bovine arch in concordance with other structural heart defects such as VSD, ASD, and coarctation. 8,12 The most important predisposing factor for TAD is systemic hypertension. 13 Others are older age, male gender, and other atherosclerotic risk factors.…”

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Incidence of Aortic Arch Anomalies in Patients with Thoracic Aortic Dissections

et al. 2013

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Incidence of Aortic Arch Anomalies in Patients with Thoracic Aortic Dissections

et al. 2013

View full text Add to dashboard Cite

show abstract

“…For example, examination of PAAs in Tbx1 +/− ;Raldh2 +/− double heterozygous embryos E10.5 reveals a majority of embryos show hypoplastic fourth PAAs but by E11.5, many of these recover (Ryckebusch et al, 2010). The authors of this study proposed that recovery is due to the effect of retinoic acid on local signals (such as deletion syndrome than in the general population (Katz et al, 2006;Wells et al, 1993). 22q11.2 deletion syndrome is the most frequent gene deletion disorder in humans affecting 1 in 4,000 live births and results in a variety of abnormalities of the outflow tract of the heart and the aortic arch (McDonald-McGinn et al, 2015).…”

Section: F I G U R Ementioning

confidence: 82%

Reduced maternal vitamin A status increases the incidence of normal aortic arch variants

Sugrue

Zohn

2019

Genesis

View full text Add to dashboard Cite

While common in the general population, the developmental origins of "normal" anatomic variants of the aortic arch remain unknown. Aortic arch development begins with the establishment of the second heart field (SHF) that contributes to the pharyngeal arch arteries (PAAs). The PAAs remodel during subsequent development to form the mature aortic arch and arch vessels. Retinoic acid signaling involving the biologically active metabolite of vitamin A, plays a key role in multiple steps of this process. Recent work from our laboratory indicates that the E3 ubiquitin ligase Hectd1 is required for full activation of retinoic acid signaling during cardiac development. Furthermore, our study suggested that mild alterations in retinoic acid signaling combined with reduced gene dosage of Hectd1, results in a benign aortic arch variant where the transverse aortic arch is shortened between the brachiocephalic and left common carotid arteries. These abnormalities are preceded by hypoplasia of the fourth PAA. To further explore this interaction, we investigate whether reduced maternal dietary vitamin A intake can similarly influence aortic arch development.Our findings indicate that the incidence of hypoplastic fourth PAAs, as well as the incidence of shortened transverse arch are increased with reduced maternal vitamin A intake during pregnancy. These studies provide new insights as to the developmental origins of these benign aortic arch variants. K E Y W O R D Saortic arch development, congenital heart defects, Hectd1, retinoic acid, vitamin A deficiency

show abstract

Vascular Rings and Slings

Powell¹

2016

Echocardiography in Pediatric and Congenital Heart Disease

View full text Add to dashboard Cite

Common Origin of the Innominate and Carotid Arteries: Prevalence, Nomenclature, and Surgical Implications

Cited by 19 publications

References 5 publications

Incidence of Aortic Arch Anomalies in Patients with Thoracic Aortic Dissections

Incidence of Aortic Arch Anomalies in Patients with Thoracic Aortic Dissections

Reduced maternal vitamin A status increases the incidence of normal aortic arch variants

Vascular Rings and Slings

Contact Info

Product

Resources

About