Common methodological pitfalls in ICI pneumonitis risk prediction studies
Yichen K. Chen,
Sarah Welsh,
Ardon M. Pillay
et al.
Abstract:BackgroundPneumonitis is one of the most common adverse events induced by the use of immune checkpoint inhibitors (ICI), accounting for a 20% of all ICI-associated deaths. Despite numerous efforts to identify risk factors and develop predictive models, there is no clinically deployed risk prediction model for patient risk stratification or for guiding subsequent monitoring. We believe this is due to systemic suboptimal approaches in study designs and methodologies in the literature. The nature and prevalence o… Show more
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