Common genetic variants associated with urinary phthalate levels in children: a genome-wide study
Mariona Bustamante,
Laura Balagué,
Zsanett Buko
et al.
Abstract:Introduction:Phthalates, or dieters of phthalic acid, are a ubiquitous type of plasticizer used in a variety of common consumer and industrial products. They act as endocrine disruptors and are associated with increased risk for several diseases. Once in the body, phthalates are metabolized through partially known mechanisms, involving phase I and phase II enzymes.Objective:In this study we aimed to identify common single nucleotide polymorphisms (SNPs) and copy number variants (CNVs) associated with the metab… Show more
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