1989
DOI: 10.1016/0165-4608(89)90136-2
|View full text |Cite
|
Sign up to set email alerts
|

Common fragile sites in chromosomes of bone marrow cells and peripheral blood lymphocytes from healthy persons and leukemia patients

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
2

Citation Types

0
9
0

Year Published

1991
1991
2005
2005

Publication Types

Select...
9

Relationship

1
8

Authors

Journals

citations
Cited by 14 publications
(9 citation statements)
references
References 15 publications
0
9
0
Order By: Relevance
“…Furuya et al (1989) described a CFS that accounts for 13.4% of the total BCG scored in human bone marrow cells of healthy persons at 4q21-25 (the most expressed in these cells). Recurrent BCG were also localized at 4q21 or 4q23 in other types of cells (Murano et al, 1989;Caporossi et al, 1995;Gericke et al, 1996;Simonic et al, 1997).…”
Section: Discussionmentioning
confidence: 99%
“…Furuya et al (1989) described a CFS that accounts for 13.4% of the total BCG scored in human bone marrow cells of healthy persons at 4q21-25 (the most expressed in these cells). Recurrent BCG were also localized at 4q21 or 4q23 in other types of cells (Murano et al, 1989;Caporossi et al, 1995;Gericke et al, 1996;Simonic et al, 1997).…”
Section: Discussionmentioning
confidence: 99%
“…8q22 is a common site of chromosome fragility (Furuya et al, 1989). The translocation t(8 : 21) (q22;q22) is a typical chromosomal abnormality associated with acute myeloid leukemia (Rabbitts, 1994).…”
Section: Discussionmentioning
confidence: 99%
“…Evidence, both positive (Tedeschi et aI., 1987;Furuya et al, 1989) and negative (Rao et al, 1988;Green et al, 1988;Porfirio et al, 1989;Kampmann et al, 1990), with respect to association of the expressivity of common fragile site with cancer has been reported with but a small number of subjects. In the present study, we tested the expression of fra(3)(pl4.2) in a large number of unselected hospital patients, including cancers of the various organs.…”
Section: Discussionmentioning
confidence: 99%
“…The present study con-ducted a similar survey on patients of various diseases. Whereas there have been a few papers which showed a positive correlation with some cancers (Tedeschi et al, 1987;Furuya et al, 1989), the common fragile sites are not generally considered as having any biological significance.…”
Section: Introductionmentioning
confidence: 99%