Common bile duct obstruction due to a duodenal gastrinoma in a dog

M, Vergine; Pozzo, Sergio; Pogliani, E; Rondena, M.; Roccabianca, P.; Bertazzolo, Walter

doi:10.1016/j.tvjl.2004.04.013

Cited by 25 publications

(18 citation statements)

References 5 publications

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“…1,3,[8][9][10][11][12] An underlying cause was reported for 16 of those dogs, of which 12 had chronic pancreatitis, 2 had neoplasia (duodenal gastrinoma and pancreatic adenocarcinoma), 1 had a pseudocyst, and 1 had cholelithiasis. 1,3,[8][9][10][11][12] An underlying cause was reported for 16 of those dogs, of which 12 had chronic pancreatitis, 2 had neoplasia (duodenal gastrinoma and pancreatic adenocarcinoma), 1 had a pseudocyst, and 1 had cholelithiasis.…”

Section: Discussionmentioning

confidence: 99%

Cholecystoenterostomy for treatment of extrahepatic biliary tract obstruction in cats: 22 cases (1994–2003)

Buote¹,

Mitchell²,

Penninck³

et al. 2006

javma

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Section: Discussionmentioning

confidence: 99%

Cholecystoenterostomy for treatment of extrahepatic biliary tract obstruction in cats: 22 cases (1994–2003)

Buote¹,

Mitchell²,

Penninck³

et al. 2006

javma

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“…Gastrinomas are neuroendocrine tumors that secrete gastrin. Gastrinomas usually are located in the pancreas, but a gastrinoma has been documented in the duodenum of a dog . Dogs with gastrinomas typically develop vomiting, weight loss, anorexia, lethargy, diarrhea, polydipsia, and melena .…”

Section: Introductionmentioning

confidence: 99%

Normal Dogs Treated with Famotidine for 14 days Have Only Transient Increases in Serum Gastrin Concentrations

Mordecai¹,

Sellon

Mealey

2011

Veterinary Internal Medicne

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Background: In people, serum gastrin concentrations increase in response to administration of H 2 receptor antagonists, but the effect of famotidine administration on serum gastrin concentrations has not been evaluated in dogs.Objectives: To determine if serum gastrin concentrations increase in response to 14 days of famotidine treatment and the time needed to return to baseline after discontinuation of famotidine; define stability of gastrin in samples held at room temperature.Animals: Eleven healthy dogs were included in part A (famotidine treatment) and 7 healthy dogs in Part B (serum gastrin stability). In part A, famotidine (0.5 mg/kg PO q12h) was administered for 14 days. Fasting blood samples were collected on days 0, 3, 7, 11, 14, 16, 18, 20, and 22. In part B, blood was collected after a 12-hour fast. Gastrin concentrations in serum samples held at room temperature for 30 minutes after sampling were compared to concentrations in samples held at room temperature for 150 minutes after sampling.Results: Serum gastrin concentrations increased by day 3 of famotidine administration and returned to baseline concentrations in all dogs by day 14 despite continued famotidine administration. Serum gastrin concentrations were lower (20% mean decrease; P = .0005) in samples held at room temperature for 150 minutes.Conclusions and Clinical Importance: After 14 days of famotidine administration, clinically healthy dogs have normal serum gastrin concentrations. In a dog with clinical features consistent with gastrinoma, chronic famotidine administration is unlikely to contribute to increases in serum gastrin concentrations.

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“…In severe cases of nonmalignant disease or with longstanding involvement, there may be greater wall thickening with disruption or loss of the wall layers. 43 Certain neoplastic diseases can also diffusely thicken the stomach wall. If gastric ulcers are present, ulcer craters and more localized wall thickening may be seen at the site of the ulcer (Figure 12-16).…”

Section: Diffuse Wall Thickeningmentioning

confidence: 99%

“…43 Leiomyoma of the small intestine in a 7-year-old dog. A, Hypoechoic, nearly anechoic eccentric mass in the small intestine is identified (2.61 × 1.50 cm between electronic cursors).…”

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confidence: 99%