Commercially Available Crystalloids and Colloids

Vennari, Marialuisa; Benedetto, M. A.

doi:10.1007/978-88-470-2661-2_18

Cited by 3 publications

(6 citation statements)

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“…Metabolism is not dependent on intact liver function and does not affect blood glucose or insulin concentration [10,11]. Metabolism is not oxygen-dependent and effective at low pH values [12][13][14][15].…”

Section: Introductionmentioning

confidence: 99%

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Influence of acetate containing fluid versus lactate containing fluid on acid-base status, electrolyte level, and blood lactate level in dehydrated dogs

Heitland¹,

Klein-Richers

Hartmann

et al. 2021

Vet World

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Background and Aim: Acetate or lactate buffered, balanced isotonic rehydration fluids are commonly used for fluid therapy in dogs and may influence acid-base and electrolyte status. This study aimed to assess acid-base status, electrolyte levels, and lactate levels in dehydrated dogs after receiving acetate or lactate-containing intravenous rehydration fluids. Materials and Methods: In this prospective, randomized study, 90 dehydrated dogs were included and randomized to receive acetate [Sterofundin® ISO B. Braun Vet Care (STERO), Germany) or lactate (Ringer-Lactat-Lösung nach Hartmann B. Braun Vet Care (RL), Germany] containing intravenous fluids for rehydration. The exclusion criteria were as follows: Age <6 months, liver failure, congestive heart failure, and extreme electrolyte deviation. Physical examination, venous blood gas, and lactate levels were analyzed before and after rehydration. The two groups were compared using t-test and Chi-square test. The significance level was set at p≤0.05. Results: Post-rehydration heart rate decreased in the STERO group (p<0.001) but not in the RL group (p=0.090). Lactate levels decreased in both groups STERO (p<0.001) and in group RL (p=0.014). Sodium and chloride levels increased during rehydration in group STERO (p<0.001; p<0.001) and group RL (p=0.002; p<0.001). There was a larger decrease in lactate levels in group STERO compared to group RL (p=0.047). Conclusion: Both solutions led to a mild increase in sodium and chloride levels and decreased lactate levels. The acetate-containing solution had an inferior effect on the decrease in lactate level.

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Section: Introductionmentioning

confidence: 99%

“…Lactate degradation is oxygen dependent, and oxygen consumption increases during lactate metabolism. During hypoxic conditions, lactate metabolism is limited [12][13][14][15]. Lactate is metabolized to some extent through the Cori cycle during ATP consumption, leading to the synthesis of glucose and increased energy consumption [17].…”

Section: Introductionmentioning

confidence: 99%

Influence of acetate containing fluid versus lactate containing fluid on acid-base status, electrolyte level, and blood lactate level in dehydrated dogs

Heitland¹,

Klein-Richers

Hartmann

et al. 2021

Vet World

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show abstract

“…SF is a balanced isotonic solution for intravenous infusion with electrolyte composition very similar to plasma (Na-140, k-4.0, Ca -2.5, Mg -1, and Cl -127 mmol/l). It also has a potential base excess of zero and contains acetate (24 mmol/l) and maleate (5mmol/l) which is widely metabolized in all organs and muscles, resulting in low oxygen consumption which is 1.2L oxygen per liter solution [19][20] . RL contains sodium (130 mmol/L), potassium (5 mmol/L), calcium and magnesium (both at 1 mmol/l), chloride (112 mmol/L), and lactate (27 mmol/L).…”

Section: Discussionmentioning

confidence: 99%

A study on effect of lactate versus acetate-based intravenous fluids on acid-base balance in patients undergoing free flap reconstructive surgeries in India

Chhabra¹,

Chhabra²

2019

Int. J. Surg. Sci.

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Introduction: Fluid therapy is very important in managing the recovery of patients from major surgery and trauma. Postoperative fluid management comprises maintenance of fluid, replacement of on-going losses and correction of anemia or hypovolemia. Use of lactated intravenous fluids during long surgeries could cause lactate accumulation and lactic acidosis. We evaluated the comparative effects of administration of lactated versus no lactated solutions on serum lactate levels in patients undergoing free flap surgeries. Material and Methods: This was a prospective study conducted over a period of 3 years. 72 patients undergoing major head and neck surgeries with free flap reconstruction were recruited. No patient was forced to be a part of the study. Patients with hepatic and renal derangement, congestive cardiac failure, diabetics, and those unwilling to participate after explanation of the protocol were not included in the study. Result: Mean age of the patients in years in Groups SF and RL was 54.5±18.1 versus 48.2±16.5 (P=0.168) and weight in kg was 64.2±9.8 vs. 59.3±13.1, P =0.196, respectively, hence the demographic variables in both groups were comparable. The distribution of gender and physical status were also comparable. Conclusion: we conclude that the intraoperative use of Sterofundin is comparable or even better than Ringer's Lactate in terms of preservation of acid-base and electrolyte balance, avoidance of hypo/hyperglycaemia and cardiovascular stability in patients undergoing moderate to major surgery.

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“…It also has a potential base excess of zero and contains acetate (24 mmol/l) and maleate (5 mmol/l) which is widely metabolized in all organs and muscles, resulting in low oxygen consumption which is 1.2 L oxygen per liter solution. [ 10 11 ]…”

Section: Discussionmentioning

confidence: 99%

“…The lactate in RL was added to reduce the chloride content, thereby reducing the incidence of hyperchloremic metabolic acidosis which usually occurs after infusion of large volumes of normal saline during the intraoperative period. [ 10 11 ]…”

Section: Discussionmentioning

confidence: 99%

Effect of lactate versus acetate-based intravenous fluids on acid-base balance in patients undergoing free flap reconstructive surgeries

Rajan

Srikumar

Tosh

et al. 2017

J Anaesthesiol Clin Pharmacol

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Commercially Available Crystalloids and Colloids

Cited by 3 publications

References 0 publications

Influence of acetate containing fluid versus lactate containing fluid on acid-base status, electrolyte level, and blood lactate level in dehydrated dogs

Influence of acetate containing fluid versus lactate containing fluid on acid-base status, electrolyte level, and blood lactate level in dehydrated dogs

A study on effect of lactate versus acetate-based intravenous fluids on acid-base balance in patients undergoing free flap reconstructive surgeries in India

Effect of lactate versus acetate-based intravenous fluids on acid-base balance in patients undergoing free flap reconstructive surgeries

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