Commercialisation of GM Crops: Comparison of Regulatory Frameworks

Vanga, Siva Reddy; Medaglia, Jorgé Cabrera

doi:10.1007/978-1-4614-5797-8_837

Cited by 2 publications

(1 citation statement)

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“…With the advent of recombinant-DNA (r-DNA) techniques applied to the genetic modification of organisms for agri-food uses, governments developed ad hoc regulatory frameworks for the so-called "modern biotechnology" [16,7,79]. Typically, such ad hoc regulation does not replace but supplement other regulations of broad applicability to organisms of agricultural use and the foodstuffs derived from them.…”

Section: The Established Regulation Of "Modern Biotechnology"mentioning

confidence: 99%

Regulatory Assessment of Off-Target Changes and Spurious DNA Insertions in Gene-Edited Organisms for Agri-Food Use

Lema

2021

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Worldwide, an increasing number of regulatory systems have begun to consider applications for the authorization of activities involving gene-edited organisms for agri-food use. Although a handful of countries have made advances in establishing regulatory criteria and gathering practical experience in this regard, there is still a general need for regulatory cooperation concerning capacity building and development of harmonized criteria. Consequently, many biotechnology regulators need to quickly become more acquainted with the numerous technological possibilities enclosed under the concept of "gene editing", and to incorporate criteria for their regulatory assessment. This article contains a simplified introduction to the state of the art in genome editing, described from a regulatory perspective. In particular, two issues of higher practical importance are covered in detail, namely, off-target effects and unintended DNA insertions. The detailed review of current evidence regarding those issues serves as the basis for proposing concrete regulatory criteria to address them. doi: 10.21423/jrs-v09i1lema

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Section: The Established Regulation Of "Modern Biotechnology"mentioning

confidence: 99%