Comments on Rahmati et al., The global impact of COVID‐19 pandemic on the incidence of pediatric new‐onset type 1 diabetes and ketoacidosis: A systematic review and meta‐analysis. J Med Virol. 2022; 1‐16 (doi: 10.1002/jmv.27996)

Rosenbauer, Joachim; Stahl‐Pehe, Anna; Schlesinger, Sabrina; Kuß, Oliver

doi:10.1002/jmv.28272

Cited by 2 publications

(1 citation statement)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition, in this meta-analysis, the change in incidence rates between 2019 and 2020 was compared and it was shown that the global risk of pediatric new-onset T1D, diabetic ketoacidosis (DKA), and severe DKA increased. 10 , 11 However, regional differences are noteworthy. It is seen that this increase is more pronounced in countries, which have a relatively high incidence of T1D.…”

Section: Introductionmentioning

confidence: 99%

Change in the Frequency of Diabetic Ketoacidosis in Children with Newly Diagnosed Type 1 Diabetes in the Central Anatolia Region of Turkey over the Years Before and After the Coronavirus Disease 2019 Pandemic: A Single-Center Experience

Koca,

Takcı,

Deniz

et al. 2024

Turkish Archives of Pediatrics

View full text Add to dashboard Cite

Objective: The number of admissions for severe diabetic ketoacidosis (DKA) in children with newly diagnosed type 1 diabetes (T1D) increased during the coronavirus disease 2019 pandemic. We aimed to investigate whether there has been a change in this situation in recent years. Materials and Methods: All children with T1D who were diagnosed in our tertiary hospital between 2019 and 2023 were included. Plasma insulin, C-peptide, hemoglobin A1c (HbA1c), and antibodies against thyroid peroxidase, thyroglobulin, insulin, islet cell, glutamic acid decarboxylase, tissue transglutaminase IgA, and endomysium IgA were measured. Results: The frequency of moderate–severe acidosis at admission, which increased after pandemic period compared to the pre-pandemic period, returns to its previous levels over time but still shows a statistical difference compared to the pre-pandemic period ( P = .012). Age, blood gas pH and HCO 3 level, C-peptide, HbA1c, and length of stay of children at the time of admission were compared year by year (years 2019-2023). No statistical differences were observed ( P = .509, P = .181, P = .069, P = .469, P = .346, P = .946), respectively. A significant difference was observed in venous glucose ( P < .001) and insulin ( P = .001) according to years. Also, no significant difference was found about the degree of acidosis according to age ( P = .334). Conclusion: Although the frequency of DKA in children with newly-diagnosed T1D increased in the first years of the pandemic, it has been decreasing over the years toward pre-pandemic levels. The frequency of DKA is still higher than the pre-pandemic period.

show abstract

Section: Introductionmentioning

confidence: 99%