Comments on ‘Prevalence of contact allergy in the general population in different European regions’ and ‘Prevalence of fragrance contact allergy in the general population of five European countries: a cross-sectional study’

Meding, Birgitta; Järvholm, Bengt

doi:10.1111/bjd.14641

Cited by 5 publications

(1 citation statement)

References 4 publications

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“…The present comparison benefits from a high degree of methodological standardization in the EDEN study, 6 and a presumably largely representative sample, compared to a previous similar comparison in the region of Augsburg, Bavaria (Germany; KORA study), 4 where, due to the sampling strategy employed, some selection bias by design may be suspected 1 . However, the EDEN study also may not be free of some selection bias, too: participation in initial recruitment had been reported to range between 20.3% and 50.7% in different regions, 1,17,18 and a participation of less than 70% is considered to jeopardize non‐selectiveness 1 . However, the age‐ and sex‐stratified replacement sampling used 18 is capable of evening out numerical deficits appearing in certain strata, and confounding associated with these important variables.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of contact allergies in the population compared to a tertiary referral patch test clinic in Jena/Germany

et al. 2021

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Background The contact allergy prevalences in patch‐tested patients are usually higher than those in the population, owing to morbidity‐driven selection. Objectives To examine the differences between two samples, one from the population, one from the patch test clinic, in one area of Germany (Jena, Thuringia). Methods Between August 2008 and October 2011, a total of 519 participants of the population‐based european dermato‐epidemiology network (EDEN) fragrance study were patch tested in Jena using a TRUE Test baseline series extended with some pet.‐based (fragrance) allergen preparations. Between 2007 and 2012 (inclusive), 1906 routine patients were patch tested for suspected allergic contact dermatitis (ACD) in the Jena University Hospital Department; of these 1694 (83.2%) with the German baseline series using pet./aq.‐based, investigator‐loaded allergens. Results In the population (clinical) sample, 19.6% (41.1%) were sensitized to at least one of the allergens considered. The most common baseline series allergens in the population/clinical sample were nickel (10.5%/13.2%), fragrance mix (FM) II (2.9%/6.7%), FM I (2.3%/8.3%), and cobalt (1.6%/5%). The clinical sample was slightly older (71.5% vs 55.9% age 40+) and included less males (36% vs 49.3%). Conclusions Results are quite similar, although prevalences are usually higher in the clinical setting, with the exception of p‐tert‐butylphenol formaldehyde resin.

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