As experiments are increasingly able to probe the quantum dynamics of systems with many degrees of freedom, it is interesting to probe fundamental bounds on the dynamics of quantum information. We elaborate on the relationship between one such bound-the Lieb-Robinson bound-and the butterfly effect in strongly coupled quantum systems. The butterfly effect implies the ballistic growth of local operators in time, which can be quantified with the "butterfly" velocity v B . Similarly, the Lieb-Robinson velocity places a state-independent ballistic upper bound on the size of time evolved operators in nonrelativistic lattice models. Here, we argue that v B is a state-dependent effective Lieb-Robinson velocity. We study the butterfly velocity in a wide variety of quantum field theories using holography and compare with freeparticle computations to understand the role of strong coupling. We find that v B remains constant or decreases with decreasing temperature. We also comment on experimental prospects and on the relationship between the butterfly velocity and signaling. DOI: 10.1103/PhysRevLett.117.091602 In relativistic systems with exact Lorentz symmetry, causality requires that spacelike-separated operators commute. In nonrelativistic systems, there is no analogous notion: a local operator Vð0Þ at the origin need not commute with another local operator Wðx; tÞ at position x at a later time t, even if the separation is much larger than the elapsed time jxj ≫ t. This can be understood by considering the Baker-Campbell-Hausdorff formula for the expansion of Wðx; tÞ ¼ e iHt WðxÞe −iHt ,where H is the Hamiltonian which is assumed to consist of bounded local terms. As long as there is some sequence of terms in H that connect the origin and point x (and absent any special cancellations), the operator Wðx; tÞ will generically fail to commute with Vð0Þ. This does not necessarily imply that the magnitude commutator ½Wðx; tÞ; Vð0Þ between distance operators must be large. A bound of Lieb and Robinson [1], along with many subsequent improvements [2][3][4], limits the size of commutators of local operators separated in space and time, even in nonrelativistic systems. In terms of the Heisenberg operator Wðx; tÞ at position x and time t and an operator V at the origin of space and time, the bound reads ∥½Wðx; tÞ; Vð0Þ∥where K 0 and ξ 0 are constants, ∥ · ∥ indicates the operator norm, and v LR is the Lieb-Robinson velocity. The growth of the commutator is controlled by v LR , which is a function of the parameters of the Hamiltonian. Hence, although operators separated by a distance x may cease to exactly commute for any t > 0, the Lieb-Robinson bound implies that their commutator cannot be Oð1Þ until t ≳ x=v LR . Thus, the Lieb-Robinson velocity provides a natural notion of a "light" cone for nonrelativistic systems. Even for relativistic systems, where causality implies that the commutator of local operators must be exactly zero for t < x (in this Letter we have set the speed of light to unity, c ¼ 1), the Lieb-Robinson cone, ...