Commentary on Gender Differences in Prevalence, Treatment, and Quality of Life of Patients with Chronic Rhinosinusitis

Ference, Elisabeth H.; Tan, Bruce K.; Hulse, Kathryn E.; Chandra, Rakesh K.; Smith, Sean B.; Kern, Robert C.; Conley, David B.; Smith, Stephanie Shintani

doi:10.2500/ar.2015.6.0120

Cited by 53 publications

(60 citation statements)

References 54 publications

(92 reference statements)

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“…While these studies only evaluated patients with confirmed diagnosis of CRS, our study is unique in that it demonstrates a significant difference primarily among those patients with negative imaging. This may support previously noted gender differences in health utility or misdiagnosis and workup for issues such as “sinus headache”; women are over 3 times more likely to complain of “sinus headache” than men …”

Section: Discussionsupporting

confidence: 82%

Assessing the clinical applicability of prior head imaging in patients with chronic rhinosinusitis

Bhalla

McCann

Sykes

et al. 2017

Int Forum Allergy Rhinol

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Section: Discussionsupporting

confidence: 82%

Assessing the clinical applicability of prior head imaging in patients with chronic rhinosinusitis

Bhalla

McCann

Sykes

et al. 2017

Int Forum Allergy Rhinol

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“…In terms of sex‐based differences, several studies indicate that adult females are more susceptible to chronic maxillary sinusitis (Chen et al, ; Shashy et al, ; Falagas et al, ; Busaba et al, ; Bernstein et al, ; Schiller et al, ; Ference et al, ; but see several studies specifically regarding Asian populations Min et al, ; Chung et al, ; Shi et al, ). Studies have further suggested that anatomic variants in the nasal and paranasal sinuses can predispose individuals to various ailments, including sinusitis (see Herman et al, ).…”

Section: Discussionmentioning

confidence: 99%

Anatomical Variation in Maxillary Sinus Ostium Positioning: Implications for Nasal‐Sinus Disease

Butaric

Wadlé

Gascon

et al. 2018

The Anatomical Record

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Among humans, superiorly located maxillary sinus ostia (MSO) result in drainage complications and maxillary sinus (MS) disease. While previous studies investigate maxillary sinusitis frequency or MSO‐position relative to specific nasal landmarks, few explore MSO‐position to overall MS dimensions. This study investigates whether MSO‐position relates to MS size/shape and if sex‐based differences exist. Twenty‐nine landmarks, placed on magnetic resonance images (MRIs) of 109 individuals (males = 57; females = 52), captured maximum dimensions of the cranium, MS, nasal cavity, and MSO‐position relative to the MS floor (MSO_MSF) and nasal floor (MSO_NCF). Landmark coordinates were used to calculate centroid sizes and 13 linear distances; distances were size standardized by cranial centroid‐size. Principal components analysis (PCA) on 3D‐coordinates indicates that variation in MSO‐position relates to superior–inferior MS positioning within the face (PC1 22% variance) and MS height (PC2 12% variance). Regression analyses indicate that MS size (r2 = 0.502; P < 0.001) and height (r2 = 0.589; P < 0.0001) strongly contribute to MSO_MSF: larger, taller MSs exhibit greater MSO_MSFs. Sex‐based differences were not evident in PC shape‐analyses nor among size‐standardized dimensions. However, Mann–Whitney U‐tests indicate females have absolutely smaller MSs (P = 0.001) and MSO_MSF distances (P = 0.001). Further, regressions indicate females exhibit lower MSO_MSFs for a similar MS height. Overall, MSOs superiorly placed relative to the MS floor correlate with larger, taller MSs and/or sinuses positioned inferiorly within the face. While craniofacial surgeons/clinicians should be aware of potential sex‐based differences in MS size and MSO position, this study does not suggest that higher incidences of female‐reported sinusitis relate to sex‐based differences in MS anatomy. Anat Rec, 302:917–930, 2019. © 2018 Wiley Periodicals, Inc.

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“…This contrasts with analysis of recent data that indicates that CRS is more prevalent in female than male patients. 17 Several explanations for the apparent relationship between social determinants of health and rhinology utilization are possible. First, more economically advantaged patients (higher income, insurance coverage) likely have greater access to medical care, particularly specialists.…”

Section: Discussionmentioning

confidence: 99%

The Relationship between Social Determinants of Health and Utilization of Tertiary Rhinology Care

Samuelson

Chandra

Turner

et al. 2017

Am J Rhinol�Allergy

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Results of this study indicated that some social determinants of health (race, income, educational level, insurance status) do affect utilization of tertiary rhinology services. Higher utilization among those with higher income and educational attainment are contradictory to the data, which indicated that lower socioeconomic status was associated with a higher CRS rate. Further study is required to understand the disparities in rhinology utilization rates.

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Commentary on Gender Differences in Prevalence, Treatment, and Quality of Life of Patients with Chronic Rhinosinusitis

Abstract: ABSTRACT

Cited by 53 publications

References 54 publications

Assessing the clinical applicability of prior head imaging in patients with chronic rhinosinusitis

Assessing the clinical applicability of prior head imaging in patients with chronic rhinosinusitis

Anatomical Variation in Maxillary Sinus Ostium Positioning: Implications for Nasal‐Sinus Disease

The Relationship between Social Determinants of Health and Utilization of Tertiary Rhinology Care

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