2009
DOI: 10.1016/j.jalz.2009.01.012
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Commentary on “A roadmap for the prevention of dementia II. Leon Thal Symposium 2008.” Primary prevention of dementia in Alzheimer's disease: A perspective from prevention research in cardiovascular disease and stroke

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“…The practical value of delaying the progression of dementia may be viewed as limited, particularly if the cost of therapy is high. Slowing the rate of progression may not be viewed as necessarily beneficial, since the state of being demented itself is a seriously impaired and generally undesirable one (28). Patients may show no symptomatic improvement and cannot internally validate the decrease in rate of disease progression.…”
Section: Challenges Unique To Defining Value In Ad Disease Modifying mentioning
confidence: 99%
“…The practical value of delaying the progression of dementia may be viewed as limited, particularly if the cost of therapy is high. Slowing the rate of progression may not be viewed as necessarily beneficial, since the state of being demented itself is a seriously impaired and generally undesirable one (28). Patients may show no symptomatic improvement and cannot internally validate the decrease in rate of disease progression.…”
Section: Challenges Unique To Defining Value In Ad Disease Modifying mentioning
confidence: 99%