Commentary: Maintenance with hypomethylating agents after allogeneic stem cell transplantation in acute myeloid leukemia and myelodysplastic syndrome: A systematic review and meta-analysis

Abstract

Agha I ( ) Commentary: Maintenance with hypomethylating agents after allogeneic stem cell transplantation in acute myeloid leukemia and myelodysplastic syndrome: A systematic review and meta-analysis.

Editorial: Hematopoietic stem cell transplantation: back to the future

“…In the HMA maintenance group, the overall survival and the relapse-free survival were superior; the cumulative incidence of relapse and non-relapse mortality were lower than in the observation group. However, some limitations of this study were reported in a commentary by Beauvais et al ( 9 ), who believed an inaccurate approach to data design and analyses led to an immortal time bias. These authors argued that only a randomized study can demonstrate a definitive conclusion.…”