“…Mortality at the one-year follow-up is high (around 50%), underscoring the importance of patient selection and of performing these interventions in experienced centers. When comparing the three approaches of TMVR for ViMAC, transatrial appears to have the best results, with one-year rates of mortality at 35% (25% in the latest series) [ 16 , 22 , 23 ], compared to those of transapical (57%) and transseptal (63%), and higher technical success rates (89% vs. 71% and 65%, respectively). The most important adverse event is the obstruction of the LVOT, with a hazard ratio for mortality of 2.87 (95% confidence interval 1.66–4.96) [ 19 ], so this must always be anticipated by a preprocedural CT. An area below 170 mm 2 in the LVOT once the valve is implanted (“neo-LVOT”) is highly predictive of this complication ( Figure 6 ) [ 13 ].…”