Commentary: A Randomized, Double-Blind, Placebo-Controlled Trial of Metformin Treatment of Weight Gain Associated with Initiation of Atypical Antipsychotic Therapy in Children and Adolescents

Goltz, Jeffrey Samuel; Rice, Timothy

doi:10.3389/fpsyt.2017.00059

Cited by 2 publications

(1 citation statement)

References 17 publications

(22 reference statements)

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“…Although it is more accurate to use body fat rate to reflect the effect of fat reduction, waist circumference deserves more attention as a more convenient auxiliary index. In Sacher's study [20] the waist circumference of children in the intervention group decreased by 4.1 cm, which is in line with the outcomes reported in two other randomised studies [40,41] and two studies on the efficacy of obesity drugs [42,43]. Conversely, the present results revealed that aquatic training does not improve waist circumference, which might be due to the low number of included studies.…”

Section: Discussionsupporting

confidence: 90%

Effects of Aquatic Training on Waist Circumference and Body Composition among Children: A Meta-analysis

Zhou¹,

Othman²,

Khairani³

2022

Exerc Sci

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PURPOSE: Aquatic training assists in reducing the risk of exercise on joints among children. This systematic review evaluated the effectiveness of aquatic training for children from the perspective of body composition.METHODS: A meta-analysis was performed to determine the potential impact of aquatic training in children. Four databases, namely Scopus, PubMed, Web of Science, and EBSCO, were used for the systematic search from September 2010 to November 2021. The mean differences in the data were analyzed using Stata 15.1 software with a 95% confidence interval. Outcome measures included weight, body mass index (BMI), fat percentage (Fat%), and waist circumference.RESULTS: Eleven studies, comprising eight randomized controlled trials (RCT) and three non-RCT studies, evaluating the effect of aquatic training on children were analyzed and reported. Aquatic training significantly improved the BMI (p<.01) and Fat% (p<.01) in children (ES (95% CI)=-0.23 (-0.38, -0.08) and ES (95% CI)=-0.27 (-0.45, -0.08). However, aquatic training had no significant effect on weight (p=.41), ES (95% CI)=-0.07 (-0.25, 0.10), and waist circumference (p=.11) in children, ES (95% CI)=-0.33 (-0.74, 0.08).CONCLUSIONS: Aquatic training can improve children’s BMI and body fat% but nottheir weight, waist circumference, and muscle mass. Aquatic training may be a potential exercise program for improving body composition in children.

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