Comment to: Intensive support recommendations for critically-ill patients with suspected or confirmed COVID-19 infection

Corrêa, Thiago Domingos; Matos, Gustavo Faissol Janot de; Bravim, Bruno de Arruda; Cordioli, Ricardo Luiz; Garrido, Arthur B.; Assunção, Murillo Santucci César de; Barbas, Carmen Sílvia Valente; Timenetsky, Karina Tavares; Rodrigues, Roseny dos Reis; Guimarães, Hélio Penna; Filho, Roberto Rabello; Lomar, Frederico Polito; Scarin, Farah Christina de La Cruz; Batista, Carla Luciana; Pereira, Adriano José; Guerra, João Carlos de Campos; Carneiro, Bárbara Vieira; Nawa, Ricardo Kenji; Brandão, Ricardo; Pesaro, Antônio Eduardo Pereira; Júnior, Moacyr Silva; Carvalho, Fabrício Rodrigues Torres de; Silva, Cilene Saghabi de Medeiros; Almeida, Ana Claudia Ferraz de; Franken, Marcelo; Pesavento, Marcele Liliane; Eid, Raquel Afonso Caserta; Ferraz, Leonardo José Rolim

doi:10.31744/einstein_journal/2020ce5931

Cited by 5 publications

(5 citation statements)

References 4 publications

(15 reference statements)

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“…Criteria for ICU admission and the institutional protocol for severe SARS-CoV-2 infection management have been published elsewhere. (17,18)…”

Section: Patient Managementmentioning

confidence: 99%

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Clinical characteristics and outcomes of COVID-19 patients admitted to the intensive care unit during the first year of the pandemic in Brazil: a single center retrospective cohort study

Corrêa¹,

Midega²,

Timenetsky³

et al. 2021

Einstein (São Paulo)

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Objective: To describe clinical characteristics, resource use, outcomes, and to identify predictors of in-hospital mortality of patients with COVID-19 admitted to the intensive care unit. Methods: Retrospective single-center cohort study conducted at a private hospital in São Paulo (SP), Brazil. All consecutive adult (≥18 years) patients admitted to the intensive care unit, between March 4, 2020 and February 28, 2021 were included in this study. Patients were categorized between survivors and non-survivors according to hospital discharge. Results: During the study period, 1,296 patients [median (interquartile range) age: 66 (53-77) years] with COVID-19 were admitted to the intensive care unit. Out of those, 170 (13.6%) died at hospital (non-survivors) and 1,078 (86.4%) were discharged (survivors). Compared to survivors, non-survivors were older [80 (70-88) versus 63 (50-74) years; p<0.001], had a higher Simpliﬁed Acute Physiology Score 3 [59 (54-66) versus 47 (42-53) points; p<0.001], and presented comorbidities more frequently. During the intensive care unit stay, 56.6% of patients received noninvasive ventilation, 32.9% received mechanical ventilation, 31.3% used high flow nasal cannula, 11.7% received renal replacement therapy, and 1.5% used extracorporeal membrane oxygenation. Independent predictors of in-hospital mortality included age, Sequential Organ Failure Assessment score, Charlson Comorbidity Index, need for mechanical ventilation, high flow nasal cannula, renal replacement therapy, and extracorporeal membrane oxygenation support. Conclusion: Patients with severe COVID-19 admitted to the intensive care unit exhibited a considerable morbidity and mortality, demanding substantial organ support, and prolonged intensive care unit and hospital stay.

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“…Criteria for ICU admission and the institutional protocol for severe SARS-CoV-2 infection management have been published elsewhere. (17,18)…”

Section: Patient Managementmentioning

confidence: 99%

“…The median IQR length of ICU and hospital stay was, respectively, 7 (4 to 16) days and 13 (8 to 23) days. Compared to survivors, non-survivors exhibited a higher length of ICU [15 (9-29) versus 7 (3-13) days; p<0.001] and hospital stay [19 (12-34) versus 12 (8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21) days; p<0.001] (Table 3).…”

Section: Pooled Patientsmentioning

confidence: 99%

Clinical characteristics and outcomes of COVID-19 patients admitted to the intensive care unit during the first year of the pandemic in Brazil: a single center retrospective cohort study

Corrêa¹,

Midega²,

Timenetsky³

et al. 2021

Einstein (São Paulo)

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“…Estudos apontam que valores elevados de driving pressure estão associados, significativamente, com aumento da mortalidade na UTI, sendo um parâmetro ventilatório importante na ventilação protetora 4,28…”

Section: Discussionunclassified

Ventilação protetora na síndrome do desconforto respiratório agudo causada pela COVID-19: o manejo do fisioterapeuta

et al. 2023

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Objetivos: conhecer o manejo do fisioterapeuta relacionado à ventilação protetora em pacientes com SDRA por COVID-19, listando as principais estratégias utilizadas e as barreiras encontradas para sua implementação. Métodos: estudo de campo transversal e descritivo, de caráter quantitativo, realizado no período de outubro de 2021 a abril de 2022, com fisioterapeutas de hospitais públicos e privados, na cidade de Fortaleza, que tivessem experiência com pacientes infectados pela COVID-19. Para coleta de dados, utilizou-se um formulário online viabilizado pela plataforma Google Forms. Os dados foram tabulados em planilha Microsoft Excel® 2010 e, posteriormente, transferido para o Statistical Package for the Social Sciences (SPSS®) 20.0, utilizando-se a estatística descritiva. Resultados: participaram 102 fisioterapeutas, 74,5% do gênero feminino. As principais estratégias de ventilação protetora citadas foram: volume corrente de 6 mL/Kg por peso predito, pressão de platô menor que 30 cmH2O e driving pressure menor que 15 cmH2O (93,1%), além da titulação de PEEP (68,6%) e posição prona (64,7%). Manter uma driving pressure menor que 15 cmH2O (57,8%) e discordância profissional (43,1%) foram as principais barreiras encontradas para realização da ventilação protetora. Conclusão: a ventilação protetora configura-se no uso de baixos volumes e pressões, titulação da PEEP e posição prona. A manutenção de driving pressure menor que 15 cmH2O e discordância entre os profissionais na tomada de decisão destacam-se como as principais barreiras.

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“…The criteria for ICU admission and institutional protocol for severe SARS-CoV-2 infection management have been published elsewhere. ( 14 , 15 )…”

Section: Methodsmentioning

confidence: 99%

Clinical characteristics and outcomes of patients with COVID-19 admitted to the intensive care unit during the first and second waves of the pandemic in Brazil: a single-center retrospective cohort study

Corrêa¹,

Midega²,

Cordioli³

et al. 2023

Einstein (São Paulo)

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Comment to: Intensive support recommendations for critically-ill patients with suspected or confirmed COVID-19 infection

Cited by 5 publications

References 4 publications

Clinical characteristics and outcomes of COVID-19 patients admitted to the intensive care unit during the first year of the pandemic in Brazil: a single center retrospective cohort study

Clinical characteristics and outcomes of COVID-19 patients admitted to the intensive care unit during the first year of the pandemic in Brazil: a single center retrospective cohort study

Ventilação protetora na síndrome do desconforto respiratório agudo causada pela COVID-19: o manejo do fisioterapeuta

Clinical characteristics and outcomes of patients with COVID-19 admitted to the intensive care unit during the first and second waves of the pandemic in Brazil: a single-center retrospective cohort study

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