Comment on three proposed hydrate structures

Disodium D-3-phosphoglycerate, a substrate to phosphoglycerate kinase

“…The C-C bond lengths are well within the spread of reported values (Fenn & Marshall, 1972;Shefter & Trueblood, 1965). The C(2)-O(3) length is in agreement with those in other a-hydroxy acids (Colton & Henn, 1965;Clark, 1964).…”

Anhydrous Lithium Acetate Polymorphs and Its Hydrates: Three-Dimensional Coordination Polymers

“…On the other hand, lithium acetate dihydrate has been fully characterized. The structure was determined by single crystal XRD and powder neutron diffraction, showing the formation of a one-dimensional (1D) coordination polymer. − This hydrate was also analyzed by calorimetric and spectroscopic measurements, − and it was also used to study the methyl group as a quantum rotor. Its structure has been very suitable for testing the standard theory of methyl group rotation, ,− studying the translational/rotational coupling of the hindered CH 3 quantum-rotor, and the transitions attributed to quantum-rotational tunneling by inelastic neutron scattering.…”

Drug solid solutions – a method for tuning phase transformations

“…The ferroelectric compound Rochelle salt (potassium sodium tartrate tetrahydrate) has been studied to some extent with variation in composition with substitution of ammonium as the cation. [29][30][31][32][33] These studies have shown that the physical properties can be altered via this method but a systematic approach to the substitution was not investigated. The results from our experiments are a remarkable observation as we have shown that by varying the quantities of each counterion we can tune a phase transition temperature by up to 80 K whilst retaining the same three-dimensional packing arrangement.…”