Comment on the clinical note: Acute necrotizing esophagitis in an unstable patient

Santos, Vitorino Modesto dos; Villaça, R. B.; Gouvêa, I.P.; Sa, Dotsenko

doi:10.4321/s1137-66272009000500013

Cited by 1 publication

(2 citation statements)

References 4 publications

(8 reference statements)

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“…2012, Vol. 35, Nº 1, enero-abril cations may be similar, the typical lesions of black esophagus occur in the distal third of the organ 14 , which is not the prevalent site of drug-induced esophageal injuries. In this patient, the lack of characteristic endoscopic features of black esophagus ruled out this hypothesis 14 .…”

Section: Discussionmentioning

confidence: 99%

“…Preventive measures should be based on the ingestion of drugs with about 100ml of water and in ortostatic position; ingestion of the pills or capsules at least 30 minutes before going to bed, and the use of proton pomp inhibitors if necessary 5,8,9,11 . Main differential diagnoses include infectious esophagitis, gastroesophageal reflux disorder, and acute necrotizing esophagitis (black esophagus) in erderly adults 5,14 . Both drug-induced esophageal lesions and black esophagus have been scarcely reported, and may be underestimated.…”

Section: Discussionmentioning

confidence: 99%

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Drug-induced acute esophageal lesions and use of ciprofloxacin

Santos

Carneiro²,

Cruz³

et al. 2012

Anales Sis San Navarra

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ResuMenPresentamos el caso de una mujer de 95 años con lesiones agudas del esófago que tomaba ciprofloxacino por cistitis aguda. La paciente refería dolor y sensación de cuerpo estraño retroesternal asociados con hematemesis y melena, después del segundo día de tratamiento. No había antecedentes personales de trastornos gástricos o esofágicos. La endoscopia digestiva objetivó lesiones sangrantes en el tercio medio del esófago. El uso de ciprofloxacino fue suspendido y se utilizó un inhibidor de la bomba de protones. Una semana más tarde, el aspecto endoscópico del esófago fue considerado normal. Dos únicos casos de lesiones esofágicas inducidas por ciprofloxacino han sido previamente publicados. Se presenta una revisión breve acerca de este tipo de lesiones del esófago, con énfasis a los principales factores de riesgo y medidas de prevención.Palabras clave. Anciano. Ciprofloxacino. Esofagitis inducida por drogas. Endoscopia. aBstRactWe report the case of a 95-year-old woman who had acute esophageal lesions while being treated with oral ciprofloxacin for an acute cystitis. On day 2 of treatment, she reported retroesternal pain with a globus sensation, and presented hematemesis and melena. There was no history of gastric or esophageal disturbances. An upper digestive endoscopy showed bleeding lesions on the middle third of the esophagus. Ciprofloxacin was discontinued and a proton pump inhibitor was administered. One week later, the endoscopic aspect of the esophagus was normal. Only two cases of ciprofloxacin-induced esophageal lesions have been reported previously. A short review of this kind of esophageal injuries is presented, focusing on the main risk factors and preventive measures.

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Section: Discussionmentioning

confidence: 99%