Comment on Schwartz, J.; Dockery, D.W.; Neas, M.L. 1996. Is daily mortality associated specifically with fine particles?; <i>J. Air Waste Manage. Assoc.</i> 46: 927–939

Mage, David T.

doi:10.1080/10962247.2015.1029812

Journal of the Air & Waste Management Association

2015

DOI: 10.1080/10962247.2015.1029812

|View full text |Cite

Comment on Schwartz, J.; Dockery, D.W.; Neas, M.L. 1996. Is daily mortality associated specifically with fine particles?; J. Air Waste Manage. Assoc. 46: 927–939

David T. Mage

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2017

Publication Types

Select...

Article5

Relationship

Self Cite0

Independent5

Authors

Journals

Cited by 11 publications

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Multivariate Statistical Analysis of Meteorological and Air Pollution Data in the ‘Campo De Gibraltar’ Region, Spain

Gallero

Vallejo

Umbría

et al. 2006

Environ Monit Assess

View full text Add to dashboard Cite

A complete statistical analysis of meteorological and air pollution data was carried out in the 'Campo de Gibraltar' region (in the South of Spain) from 1999 to 2002. This is a heavy industrialized area where, up to date, very few air pollution studies have been made. The main objectives of the study presented here have been the characterization of the meteorological and (gaseous and particulate) air pollution conditions in the area, and the relations between them. Multivariate statistical techniques, such as Principal Component Analysis (PCA), have been applied to the data. The results show that air quality in the area is highly dependent on meteorological conditions such as wind persistence and direction, dispersion capability of the atmosphere, and humidity content. On average, sulphur dioxide and nitrogen oxide air pollution, mainly caused by fuel-oil combustion and traffic, respectively, is not very high. However, an important number of exceedences of the limits established by the EU Directive 1999 for PM10 (particulate matter with a diameter less than 10 microm) have been observed in some points of the area. A significant percentage of these exceedences (about 22% on average) are likely caused by African dust intrusions, which usually take place from May to August. From gaseous and particulate air correlations, it seems that anthropogenic activities contribute with about 19% on average.

show abstract

Multivariate Statistical Analysis of Meteorological and Air Pollution Data in the ‘Campo De Gibraltar’ Region, Spain

Gallero

Vallejo

Umbría

et al. 2006

Environ Monit Assess

View full text Add to dashboard Cite

show abstract

Metabolomics analysis reveals that benzo[a]pyrene, a component of PM2.5, promotes pulmonary injury by modifying lipid metabolism in a phospholipase A2-dependent manner in vivo and in vitro

et al. 2017

View full text Add to dashboard Cite

Particulate matter with an aerodynamic diameter less than 2.5 μM (PM2.5) is one of the major environmental pollutants in China. In this study, we carried out a metabolomics profile study on PM2.5-induced inflammation. PM2.5 from Beijing, China, was collected and given to rats through intra-tracheal instillation in vivo. Acute pulmonary injury were observed by pulmonary function assessment and H.E. staining. The lipid metabolic profile was also altered with increased phospholipid and sphingolipid metabolites in broncho-alveolar lavage fluid (BALF) after PM2.5 instillation. Organic component analysis revealed that benzo[a]pyrene (BaP) is one of the most abundant and toxic components in the PM2.5 collected on the fiber filter. In vitro, BaP was used to treat A549 cells, an alveolar type II cell line. BaP (4 μM, 24 h) induced inflammation in the cells. Metabolomics analysis revealed that BaP (4 μM, 6 h) treatment altered the cellular lipid metabolic profile with increased phospholipid metabolites and reduced sphingolipid metabolites and free fatty acids (FFAs). The proportion of ω–3 polyunsaturated fatty acid (PUFA) was also decreased. Mechanically, BaP (4 μM) increased the phospholipase A2 (PLA2) activity at 4 h as well as the mRNA level of Pla2g2a at 12 h. The pro-inflammatory effect of BaP was reversed by the cytosolic PLA2 (cPLA2) inhibitor and chelator of intracellular Ca2+. This study revealed that BaP, as a component of PM2.5, induces pulmonary injury by activating PLA2 and elevating lysophosphatidylcholine (LPC) in a Ca2+-dependent manner in the alveolar type II cells.

show abstract

A health-based assessment of particulate air pollution in urban areas of Beijing in 2000–2004

Zhang

Song

Cai

2007

Science of The Total Environment

153

View full text Add to dashboard Cite

Particulate air pollution is a serious problem in Beijing. The annual concentration of particulate matter with aerodynamic diameter less than 10 microm (PM(10)), ranging from 141 to 166 microg m(-3) in 2000-2004, could be very harmful to human health. In this paper, we presented the mortality and morbidity effects of PM(10) pollution based on statistical data and the epidemiological exposure-response function. The economic costs to health during the 5 years were estimated to lie between US$1670 and $3655 million annually, accounting for about 6.55% of Beijing's gross domestic product each year. The total costs were apportioned into two parts caused by: the local emissions and long-range transported pollution. The contribution from local emissions dominated the total costs, accounting on average for 3.60% of GDP. However, the contributions from transported pollution cannot be neglected, and the relative percentage to the total costs from the other regions could account for about 45%. An energy policy and effective measures should be proposed to reduce particulate matter, especially PM(2.5) pollution in Beijing to protect public health. The Beijing government also needs to cooperate with the other local governments to reduce high background level of particulate air pollution.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Comment on Schwartz, J.; Dockery, D.W.; Neas, M.L. 1996. Is daily mortality associated specifically with fine particles?; J. Air Waste Manage. Assoc. 46: 927–939

Cited by 11 publications

References 16 publications

Multivariate Statistical Analysis of Meteorological and Air Pollution Data in the ‘Campo De Gibraltar’ Region, Spain

Multivariate Statistical Analysis of Meteorological and Air Pollution Data in the ‘Campo De Gibraltar’ Region, Spain

Metabolomics analysis reveals that benzo[a]pyrene, a component of PM2.5, promotes pulmonary injury by modifying lipid metabolism in a phospholipase A2-dependent manner in vivo and in vitro

A health-based assessment of particulate air pollution in urban areas of Beijing in 2000–2004

Contact Info

Product

Resources

About