Comment on “Platelet transfusion: basic aspects”

Arya, Subhash C.; Agarwal, Nirmala

doi:10.4414/smw.2014.13960

Cited by 1 publication

(2 citation statements)

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“…26 , 37 38 39 In addition, a series of differently substituted 4-hydroxyquinolones 6a – h were synthesized through a two-step procedure starting from aromatic amines 5a – h (Table 1 ). 40 41 The structures of the known compounds 4a , 4b , and 6a – h were further confirmed by comparing their physical and spectral data with those reported in the literature. 26 , 37 38 39 40 41 42 43 44…”

Section: Table 1 Synthesis Of 4-hydroxyquinolones ...mentioning

confidence: 59%

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Diastereoselective Synthesis of Carbohydrate Conjugates: Pyrano[3,2-c]quinolones

Singh,

Kumar,

Arora

et al. 2023

Synthesis

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A facile and efficient protocol for the diastereoselective synthesis of pyrano[3,2-c]quinolone carbohydrate derivatives from Perlin aldehydes and 4-hydroxyquinolones has been developed using a one-pot condensation at room temperature. In this investigation, glucose and galactose were employed as inexpensive starting materials to synthesize two sets of pyrano[3,2-c]quinolone-based carbohydrate conjugates. A total of sixteen novel compounds were successfully synthesized using this methodology in good to excellent yields. The reaction exhibited remarkable diastereoselectivity, resulting in a single diastereomeric product with a diastereomeric excess (dr) 97:3 for glucose, while a diastereomeric mixture with a diastereomeric excess (dr) 67:33 was obtained for galactose. The structural characterization of all sixteen compounds was carried out using various analytical techniques, including IR, 1H NMR, 13C NMR, 1H-1H COSY, 1H-13C HETCOR experiments, 2D NOESY NMR, and HRMS data. Additionally, the scalability of the protocol was successfully demonstrated by synthesizing one of the compounds on a gram scale, highlighting its potential for large-scale production.

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Section: Table 1 Synthesis Of 4-hydroxyquinolones ...mentioning

confidence: 59%

“…40 41 The structures of the known compounds 4a , 4b , and 6a – h were further confirmed by comparing their physical and spectral data with those reported in the literature. 26 , 37 38 39 40 41 42 43 44…”

Section: Table 1 Synthesis Of 4-hydroxyquinolones ...mentioning

confidence: 59%