Comment on “Mother‐to‐child transmission of hepatitis B virus after amniocentesis: A retrospective matched cohort study”

Lou, Haiqin; Zhou, Yi‐Hua

doi:10.1002/pd.5570

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Hepatitis B Virus1

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2022

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“…The MTCT rate was 2.5% in women who underwent amniocentesis vs 0.5% in patient without invasive procedure and all cases of vertical transmission were in patients HBeAg positive [12]. However, the results should be interpreted with caution, as the reported rate of vertical transmission in this cohort was much lower than previously shown in HBeAg positive patients where the MTCT rate is about 5-10% even in cases without an invasive procedure [13]. Moreover, the study results showed that antiviral therapy a few weeks prior to invasive testing (Tenofovir, Telbivuldine or Lamivudine) seems to reduce MTCT rates in mothers with high viral load (0% vs 14%) [12].…”

Section: Hepatitis B Viruscontrasting

confidence: 56%