“…We thank Drs. Leong et al for their comments [ 1 ] and feedback on our article [ 2 ]. In their commentary, Leong et al make the criticism that our findings were based on data from both randomized controlled trials (RCTs) and non-randomized studies of intervention (NRIS), and our findings are in disagreement with a previous meta-analysis conducted by Stroehlein et al [ 3 ] Leong et al also states that our methodological quality assessment was not clear for one of the included RCTs [ 4 ], previously conducted in our group.…”