Comment on “Chemical and Toxicological Investigations of a Previously Unknown Poisonous European Mushroom Tricholoma terreum”

Abstract

Recent findings casting doubts over the edibility of the European mushroom Tricholoma terreum are questioned on the basis of mycological and mycotoxicological considerations. Accordingly, T. terreum should remain listed among edible mushroom species.

Is the Yellow Knight Mushroom Edible or Not? A Systematic Review and Critical Viewpoints on the Toxicity of Tricholoma equestre

“…Some investigators challenge the findings by Yin et al. () and argue that T. terreum should remain listed among edible mushroom species by indicating that its content of toxic saponaceolides is ambiguously too low to exert any adverse effects on humans even without considering a potential compound loss during mushroom cooking (Davoli, Floriani, Assisi, Kob, & Sitta, ). Additionally, there is no single case of human poisoning linked to T. terreum .…”

Secondary Metabolites Isolated fromTricholomaSpecies (Basidiomycota, Tricholomatacee): A Review

“…These findings have started an interesting debate among mycologists about the actual toxicity and inedibility of T. terreum [31,32], which is still ongoing. In fact, while the myotoxicity of T. equestre to humans and mice is now well-documented [6], T. terreum is commonly eaten in Europe, mainly in France, Germany, Spain, and Italy [5].…”

“…In fact, while the myotoxicity of T. equestre to humans and mice is now well-documented [6], T. terreum is commonly eaten in Europe, mainly in France, Germany, Spain, and Italy [5]. Moreover, there are no documented cases of poisoning due to the ingestion of T. terreum in Europe and elsewhere, and the medical literature has never reported that consumption of this species induces any symptom related to rhabdomyolysis [31]. Moreover, it has been pointed out that given the amount of saponaceolides B (12) and M (23) contained in the fruiting bodies of T. terreum, toxic levels would need the ingestion of overwhelming amounts of fresh mushrooms.…”

“…Together with compounds 12 and 1826, six related C-30 terpenoids, called terreolides AF(30)(31)(32)(33)(34)(35), were isolated from the CHCl 3 /MeOH extract of dried fruiting bodies of T. terreum collected in France[8]. Terreolides have two novel structures which differ from that of saponaceolides for a different backbone of the tricyclic trioxaspiroacetal moiety.…”

Update the comments on “Study of biological activity of Tricholoma equestre fruiting bodies and their safety for human”

“…In many European countries, this species is considered as dangerous because of the cases of toxic activity, which were reported from 2001 to 2017, with a number of fatalities. Acute poisoning caused by T. equestre, including lethality, was reported from France, Spain, Poland, Lithuania and other countries [5][6][7][8][9].…”