Comment on “AC frequency characteristics of coplanar impedance sensors as design parameters” by Jongin Hong, Dae Sung Yoon, Sung Kwan Kim, Tae Song Kim, Sanghyo Kim, Eugene Y. Pak and Kwangsoo No, Lab Chip, 2005, 5, 270

Linderholm, Pontus; Renaud, Philippe

doi:10.1039/b512077b

Cited by 17 publications

(11 citation statements)

References 4 publications

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“…The cultures were kept in a 10% CO 2 atmosphere at 37 uC. The medium, cFAD (a 3 : 1 mixture of the DulbeccoVogt modification of Eagle's medium and Ham's F12 medium; Gibco BRL) supplemented with 10% fetal calf serum (Hyclone Laboratories Inc.) and 10 ng ml 21 human recombinant EGF as described previously, 23,24 was changed every 2 days. Reference cultures were cultured on commercial polystyrene culture dishes (Falcon 35-3001, Becton-Dickinson France SA).…”

Section: Cell Culturementioning

confidence: 99%

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Two-dimensional impedance imaging of cell migration and epithelial stratification

et al. 2006

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Section: Cell Culturementioning

confidence: 99%

“…23,24 They were cultured on a feeder layer of lethally irradiated mouse embryonic 3T3 fibroblasts. The cultures were kept in a 10% CO 2 atmosphere at 37 uC.…”

Section: Cell Culturementioning

confidence: 99%

Two-dimensional impedance imaging of cell migration and epithelial stratification

et al. 2006

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“…Fabrication of the devices from an anisotropic silicon master enables deep, high-throughput features in the main channel without any degradation in performance of the concentrator since its design features are channel height independent. The electrodes used as impedance sensors in our design are coplanar and rectangular as oftentimes employed in microfluidic applications (Hong et al 2005;Linderholm and Renaud 2005). The sensing electrodes in our microfluidic chips are passivated with oxide (SiO 2 ) to avoid the unwanted effects of a direct metal-electrolyte interface at the electrode surface and to maintain system stability for extended periods of time (Sanchis et al 2007).…”

Section: Introductionmentioning

confidence: 99%

“…Suehiro et al showed that impedance measurements can be effectively used to detect cells (Suehiro et al 2003a) when coupled with electroporation of cells (Suehiro et al 2003c) or with an antibody-antigen reaction (Suehiro et al 2003b). In these devices, interdigitated metallic electrodes are used to DEP trap particles, which are initially collected on the surface of the electrode (Gomez-Sjoberg et al 2005;Liu et al 2007). Formations of linear clusters (a.k.a.…”

Section: Introductionmentioning

confidence: 99%

Sample concentration and impedance detection on a microfluidic polymer chip

Sabounchi

Morales

Ponce

et al. 2008

Biomed Microdevices

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We present an on-chip microfluidic sample concentrator and detection triggering system for microparticles based on a combination of insulator-based dielectrophoresis (iDEP) and electrical impedance measurement. This platform operates by first using iDEP to selectively concentrate microparticles of interest based on their electrical and physiological characteristics in a primary fluidic channel; the concentrated microparticles are then directed into a side channel configured for particle detection using electrical impedance measurements with embedded electrodes. This is the first study showing iDEP concentration with subsequent sample diversion down an analysis channel and is the first to demonstrate iDEP in the presence of pressure driven flow. Experimental results demonstrating the capabilities of this platform were obtained using polystyrene microspheres and Bacillus subtilis spores. The feasibility of selective iDEP trapping and impedance detection of these particles was demonstrated. The system is intended for use as a front-end unit that can be easily paired with multiple biodetection/bioidentification systems. This platform is envisioned to act as a decision-making component to determine if confirmatory downstream identification assays are required. Without a front end component that triggers downstream analysis only when necessary, bio-identification systems (based on current analytical technologies such as PCR and immunoassays) may incur prohibitively high costs to operate due to continuous consumption of expensive reagents.

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“…Such closed-form analytical expressions that determine electrodynamic characteristics of coplanar electrode structures can be derived from conformal mapping methods [13]. For instance, these have been applied to determine the cell constants of planar-interdigitated conductivity sensors [14], for optimization of an electrolyte conductivity sensor [15], characterization of coplanar electrodes in microchannels [16,17], optimization for the detection of affinity binding of biomolecules [18], and to determine the electric field pattern of two-electrode structures in flow cytometer designs [19].…”

Section: Introductionmentioning

confidence: 99%

Modelling the capacitance of multi-layer conductor-facing interdigitated electrode structures

Blume¹,

Ben-Mrad²,

Sullivan³

2015

Sensors and Actuators B: Chemical

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Interdigitated electrode structures have applications in a myriad of fields and have become attractive for in-line electrochemical detection in lab-on-a-chip microsystems. Analytical models can replace complex and expensive numerical simulations to determine the capacitance of interdigitated electrode structures in cases where simple geometries can be assumed. Closed-form analytical expressions derived from Schwarz-Christoffel conformal mappings were used to determine the capacitance of multi-layer interdigitated electrode structures with an additional parallel continuous electrode. The partial-capacitance approach was reformulated to find the capacitance of multi-layer structures with non-monotonically changing permittivities. The analytical model was found to be in close agreement with finite-element simulations. The model is used for optimization of an insulated transducer for sensitive detection of surface processes.

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Comment on “AC frequency characteristics of coplanar impedance sensors as design parameters” by Jongin Hong, Dae Sung Yoon, Sung Kwan Kim, Tae Song Kim, Sanghyo Kim, Eugene Y. Pak and Kwangsoo No, Lab Chip, 2005, 5, 270

Cited by 17 publications

References 4 publications

Two-dimensional impedance imaging of cell migration and epithelial stratification

Two-dimensional impedance imaging of cell migration and epithelial stratification

Sample concentration and impedance detection on a microfluidic polymer chip

Modelling the capacitance of multi-layer conductor-facing interdigitated electrode structures

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