Let R be a commutative Noetherian ring, Φ a system of ideals of R, a ∈ Φ, M an arbitrary R-module and t a non-negative integer. Let S be a Melkersson subcategory of R-modules. Among other things, we prove that ifis in S for all i < t and for all a ∈ Φ. As consequences we study and compare vanishing, Artinianness and support of general local cohomology and ordinary local cohomology supported at ideals of its system of ideals at initial points i < t. We show that Supp R (H dim M −1 Φ (M )) is not necessarily finite whenever (R, m) is local and M a finitely generated R-module.2010 Mathematics Subject Classification. 13D45, 13E05, 14B15.