Combining predominant polarity and affective spectrum concepts in bipolar disorder: towards a novel theoretical and clinical perspective
Francesco Bartoli,
Gin S. Malhi,
Giuseppe Carrà
Abstract:This is an overview of recent advances on predominant polarity conceptualization in bipolar disorder (BD). Current evidence on its operationalized definitions, possible contextualization within the affective spectrum, along with its epidemiological impact, and treatment implications, are summarized. Predominant polarity identifies three subgroups of patients with BD according to their mood recurrencies: (i) those with depressive or (ii) manic predominance as well as (iii) patients without any preponderance (‘n… Show more
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