2022
DOI: 10.3389/fmicb.2022.990870
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Combining p-values from various statistical methods for microbiome data

Abstract: MotivationIn the field of microbiome analysis, there exist various statistical methods that have been developed for identifying differentially expressed features, that account for the overdispersion and the high sparsity of microbiome data. However, due to the differences in statistical models or test formulations, it is quite often to have inconsistent significance results across statistical methods, that makes it difficult to determine the importance of microbiome taxa. Thus, it is practically important to h… Show more

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