Combining non-invasive liquid biopsy and a methylation analysis to assess surgical risk for early esophageal cancer
Xiaole Chen,
Mingyan Li,
Yongliang Li
et al.
Abstract:Background
While the widespread use of endoscopic submucosal dissection (ESD) has significantly reduced the incidence of early esophageal cancer (ESCA), the limited ability of ESD to strip deep infiltrating esophageal lesions results in a considerable risk of intraoperative perforation. Circulating-free DNA (cfDNA) is widely used in modern tumor screening due to its non-invasive detection capabilities. A methylation analysis offers vital insights into the condition and advancement of malignancies … Show more
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