Combining functional scales and cognitive tests in screening for mild cognitive impairment at a university-based memory clinic in Brazil

Abreu, Izabella Dutra de; Nunes, Paula; Diniz, Breno S.; Forlenza, Orestes Vicente

doi:10.1590/s1516-44462008000400008

Cited by 29 publications

(17 citation statements)

References 17 publications

(11 reference statements)

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“…32,33 In a series of studies, our group addressed whether the combination of cognitive screening tests would improve the identification of MCI. Abreu et al 34 assessed whether the combination of an informantbased dementia screening test (Informant Questionnaire of Cognitive Decline in the Elderly -IQCODE) and an objective cognitive test (MMSE) would increase accuracy for identification of MCI. This combination did not significantly improve the sensitivity and specificity of each test alone in recognizing MCI cases as compared with healthy elderly subjects.…”

Section: Epidemiological Characteristics Of MCI In the Elderlymentioning

confidence: 99%

Mild cognitive impairment (part 1): clinical characteristics and predictors of dementia

Forlenza

Diniz

Stella

et al. 2013

Rev. Bras. Psiquiatr.

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Objective: To critically review and evaluate existing knowledge on the conceptual limits and clinical usefulness of the diagnosis of mild cognitive impairment (MCI) and the neuropsychological assessment and short-and long-term prognosis thereof. Methods: We conducted a systematic search of the PubMed and Web of Science electronic databases, limited to articles published in English between 1999 and 2012. Based on the search terms mild cognitive impairment or MCI and epidemiology or diagnosis, we retrieved 1,698 articles, of which 248 were critically eligible (cross-sectional and longitudinal studies); the abstracts of the remaining 1,450 articles were also reviewed. Results: A critical review on the MCI construct is provided, including conceptual and diagnostic aspects; epidemiological relevance; clinical assessment; prognosis; and outcome. The distinct definitions of cognitive impairment, MCI included, yield clinically heterogeneous groups of individuals. Those who will eventually progress to dementia may present with symptoms consistent with the definition of MCI; conversely, individuals with MCI may remain stable or return to normal cognitive function. Conclusion: On clinical grounds, the cross-sectional diagnosis of MCI has limited prognostic relevance. The characterization of persistent and/or progressive cognitive deficits over time is a better approach for identification of cases at the pre-dementia stages, particularly if these cognitive abnormalities are consistent with the natural history of incipient Alzheimer's disease.

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Section: Epidemiological Characteristics Of MCI In the Elderlymentioning

confidence: 99%

Mild cognitive impairment (part 1): clinical characteristics and predictors of dementia

Forlenza

Diniz

Stella

et al. 2013

Rev. Bras. Psiquiatr.

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“…A avaliação cognitiva e funcional dos idosos foi feita pela aplicação do Short Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) 20,21 , do Teste do Desenho do Relógio (TDR) 22 , da Escala de Demência de Blessed (EDB) 23 e do Mini-Exame do Estado Mental (MEEM) 24 . O TDR foi pontuado de acordo com as regras propostas por Shulman 22 .…”

Section: Desenho E Casuísticaunclassified

Autopercepção da saúde e desempenho cognitivo em idosos residentes na comunidade

Freitas¹,

Campos²,

Linhares³

et al. 2010

Rev. psiquiatr. clín.

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ResumoContexto: A autopercepção de saúde contempla vários aspectos da saúde física, cognição e capacidade funcional. Objetivo: Comparar idosos com e sem evidência de declínio cognitivo/demência quanto a autopercepção de saúde e variáveis sociodemográficas, destacando as variáveis associadas à autopercepção de saúde positiva e negativa dentro destes grupos. Métodos: Noventa e oito idosos residentes na comunidade foram avaliados em visitas domiciliares para este trabalho. A avaliação cognitiva e funcional foi feita por meio da aplicação do Mini-Exame do Estado Mental (MEEM), do Teste do Desenho do Relógio (TDR), da Escala de Demência de Blessed (EDB) e do Questionário do Informante de Declínio Cognitivo em Idosos (IQCODE). A autopercepção da saúde foi avaliada por intermédio de um questionário adaptado do Brazil Old Age Schedule. Resultados: Vinte e seis idosos (26%) apresentaram quadro de declínio cognitivo. Autopercepção de saúde negativa e menor participação em atividades físicas e recreativas se associaram significativamente a declínio cognitivo nesta amostra (p = 0,006, p = 0,05, p = 0,03, respectivamente). No grupo de sujeitos sem evidência de declínio cognitivo, a história prévia de eventos cerebrovasculares se relacionou à maior frequência de autopercepção negativa da saúde. Conclusão: A autopercepção negativa da saúde está relacionada ao provável diagnóstico de demência. Nos idosos com declínio cognitivo, a autopercepção positiva de saúde associa-se a quadros mais graves, refletindo possivelmente menor insight quanto ao estado mórbido. Freitas DHM, et al. / Rev Psiq Clín. 2010;37(1):32-5Palavras-chave: Autopercepção de saúde, idoso, envelhecimento, cognição, demência. AbstractBackground: The self-perception of health can approach several aspects of physical health, cognition and functional abilities. Objective: To compare elderly subjects wit and without evidence of cognitive decline in relation to health self-perception and socio-demographic variables, highlighting the variables associated with positive or negative health self-perception in these groups. Methods: Ninety eight community-dwelling subjects were assessed in this study. Cognitive and functional abilities were tested using the Mini-Mental State Examination (MMSE), the Clock Drawing Test (CDT), the Blessed Dementia Scale (BDS), and the Informant Questionnaire of Cognitive Decline in the Elderly (IQCODE). Self-perception of health evaluation was performed with the use of an adapted questionnaire of the Brazil Old Age Schedule. Results: Twenty-six subjects (26%) had evidence of cognitive decline in this sample. Negative health self-perception and lower levels of physical and leisure activity were significantly associated with cognitive decline in this sample (p = 0.006, p = 0.05, p = 0.03, respectively). In the group of subjects without evidence of dementia, history of cerebrovascular disease was associated with negative health perception. Discussion: Dementia was associated with worse health self-perception evaluation. In addition, elders with e...

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“…Evidence of functional decline was based on the scores of the Informant Questionnaire of Cognitive Disorders of the Elderly [32,33] , and on all available evidence of difficulties in the performance of basic and instrumental activities of daily living, as reported by a close relative or caregiver, as well as on the patient's self-report. The same clinical and neuropsychological assessment protocols were administered at the 1-year follow-up visit.…”

Section: Subject Assessmentmentioning

confidence: 99%

Diagnosis of Mild Cognitive Impairment Revisited after One Year

Diniz

Nunes²,

Yassuda³

et al. 2009

Dement Geriatr Cogn Disord

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Background/Aims: The diagnostic stability of mild cognitive impairment (MCI) on short-term follow-up is a key issue in the characterization of this clinical syndrome. We aim to determine the cognitive outcome after 1 year of follow-up in a cohort of older adults. Methods: Baseline clinical and neuropsychological assessments were carried out in older subjects recruited at a tertiary memory clinic. The subjects were reassessed after 1 year of follow-up with the same clinical and neuropsychological protocol. Results: A total of 115 older adults, including MCI (n = 54) and controls (n = 61), underwent baseline and follow-up evaluation. Ten subjects classified as MCI at baseline (23%) resumed normal cognitive function and 13 controls (21%) progressed to MCI upon follow-up (χ² = 0.015, d.f. = 1, p = 0.90). The subjects diagnosed as having MCI on both assessments were older (p = 0.002) and had a worse global cognitive performance according to the Cambridge Cognitive Test (p = 0.014). Conclusion: The subjects who maintain the MCI status are older and have a worse baseline cognitive performance as well as multiple cognitive deficits.

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Combining functional scales and cognitive tests in screening for mild cognitive impairment at a university-based memory clinic in Brazil

Cited by 29 publications

References 17 publications

Mild cognitive impairment (part 1): clinical characteristics and predictors of dementia

Mild cognitive impairment (part 1): clinical characteristics and predictors of dementia

Autopercepção da saúde e desempenho cognitivo em idosos residentes na comunidade

Diagnosis of Mild Cognitive Impairment Revisited after One Year

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