“…In the study of Várvölgyi et al, it was revealed that plasma osteopontin levels displayed a significant association with the probability of metastatic melanoma, which was similar to serum S100B levels. Moreover, this publication underlines that combining different biomarkers shows great clinical potential [ 7 ]. The role of aquaporin transmembrane proteins is intensively investigated in cancer biology [ 8 , 9 ].…”