Combining a microphysiological system of three organ equivalents and transcriptomics to assess toxicological endpoints for cosmetic ingredients

Indolfo, Nathalia de Carvalho; Ganzerla, Melissa Dibbernn; Doratioto, Tábata Renée; Avelino, Thayná Mendonça; Tofani, Larissa Bueno; Peroni, Luis Antonio; Rabelo, Renata Santos; Arroteia, Kelen Fabiola; Figueira, Ana Carolina Migliorini

doi:10.1039/d3lc00546a

Lab Chip

2023

DOI: 10.1039/d3lc00546a

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Combining a microphysiological system of three organ equivalents and transcriptomics to assess toxicological endpoints for cosmetic ingredients

Nathalia de Carvalho Indolfo,

Melissa Dibbernn Ganzerla,

Tábata Renée Doratioto

et al.

Abstract: A NAM, comprising a microphysiological system of three organ equivalents (skin, liver and intestine), combined with toxicological gene signature analysis, is a promising tool to assess chemical safety.

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2024

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Unveiling the intricacies of BPA and BPS: comprehensive insights into its toxic effects using a cutting-edge microphysiological system

Ganzerla,

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et al. 2024

Toxicology in Vitro

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Unveiling the intricacies of BPA and BPS: comprehensive insights into its toxic effects using a cutting-edge microphysiological system

Ganzerla,

Indolfo,

Oliveira

et al. 2024

Toxicology in Vitro

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Combining a microphysiological system of three organ equivalents and transcriptomics to assess toxicological endpoints for cosmetic ingredients

Abstract: A NAM, comprising a microphysiological system of three organ equivalents (skin, liver and intestine), combined with toxicological gene signature analysis, is a promising tool to assess chemical safety.

Cited by 1 publication

References 79 publications

Unveiling the intricacies of BPA and BPS: comprehensive insights into its toxic effects using a cutting-edge microphysiological system

Unveiling the intricacies of BPA and BPS: comprehensive insights into its toxic effects using a cutting-edge microphysiological system

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