Combined use of beta-blockers and non-dihydropyridine calcium channel blockers: possible or contraindicated?
S. S. Yakushin,
K. G. Pereverzeva
Abstract:One of the most effective medications used for various cardiac diseases and syndromes to improve symptoms and, in some cases, prognosis, are betablockers (BBs) and calcium channel blockers (CCBs). The combination of BBs and dihydropyridine CCBs has a synergistic clinical effect and is well tolerated. The clinical effects of a combination of beta blockers and non-dihydropyridine CCBs (verapamil, diltiazem) are also synergistic. However, this combination increases the incidence of side effects and complications … Show more
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