Combined treatment with beaded EWS, Gore‐tex patch and N‐butyl‐2‐cyanoacrylate for bronchial fistula: The novel “sandwich method”

Abstract

An 84‐year‐old man underwent right basal segmentectomy for primary lung cancer and developed empyema accompanied by a bronchopleural fistula (BPF). Emergency open‐window thoracotomy was performed. Although the general and nutritional conditions improved, the fistula did not close naturally, and we planned to close it 6 months after surgery. In this report, we describe, for the first time, a novel method for closing BPF using an endobronchial Watanabe spigot (EWS), polyglycolic acid (PGA) sheet and N‐butyl‐2‐cyanoacrylate (NBCA). We named this method the“sandwich method.”

Antifouling and Injectable Granular Hydrogel for the Prevention of Postoperative Intrauterine Adhesion

“…18,19 Due to its nonadhesive properties, Gore-tex requires an effective suturing to be positioned on the injured tissue surface, which also increases the complexity of surgery, especially hysteroscopic surgery. 20,21 Moreover, unlike the other two products that can be cleared or degraded, Gore-tex needs to be removed through a second surgery, which also increases the suffering of the patient. 22,23 In addition, the current film products are difficult to form conformal barriers on irregular surfaces of the human uterine cavity.…”

“…Currently, the FDA-approved products for antiadhesion are mainly physical films, such as Seprafilm, Interceed, and Gore-tex. , Although with a certain therapeutic effect, these strategies still face their own problems. Due to the lower strength of Seprafilm in hysteroscopic surgery, it is more suitable for open surgery with more complexity and more severe wounds. − The adhesion of Interceed to the tissue is significantly reduced due to the residual blood or tissue fluid on the surface of the tissue; thus, thorough hemostasis and cleaning are required during the operation. , Due to its nonadhesive properties, Gore-tex requires an effective suturing to be positioned on the injured tissue surface, which also increases the complexity of surgery, especially hysteroscopic surgery. , Moreover, unlike the other two products that can be cleared or degraded, Gore-tex needs to be removed through a second surgery, which also increases the suffering of the patient. , In addition, the current film products are difficult to form conformal barriers on irregular surfaces of the human uterine cavity.…”