Combined Technique for the Application of Micropulse Cyclophotocoagulation in Patients with Uncontrolled Glaucoma: Cyclo Mix

Abstract

Purpose To describe the outcomes of a combined technique (Cyclo Mix) in uncontrolled glaucoma cases. Materials and methods Retrospective study. The Supra 810 nm subliminal laser (Quantel Medical, Cournon d'Auvergne, France) was used. A combined technique was performed using the subliminal mode (Subcyclo) in one hemifield (power of 2,000 mW, a duty cycle of 35%, and 80–150 seconds), and the continuous wave mode (Thermo Cyclo) on the other hemifield (power of 1,000 mW, exposure time of 2 seconds per spot). The primary endpoint was the probability of surgical failure. Mean intraocular pressure (IOP) change, best-corrected visual acuity (BCVA), number of glaucoma eye drops, and complications at 6 months postoperatively were secondary outcomes. Results Twenty-three eyes from 13 patients were included. Mean age was 61.4 ± 16.7 (range: 18–78 years), and 69% were female, with a baseline IOP of 20.3 ± 5.9 (range: 13–38 mm Hg). The cumulative probability of failure was 18 and 22% on days 90 and 180, respectively. Mean IOP reduction was −25.6 ± 20.9% at 6 months. The number of glaucoma eye drops was reduced to 1.2 ± 1 (p = 0.0024) at 6 months. No statistically significant change in the mean BCVA compared with baseline at 6 months was found (p = 0.84), and no severe complications were reported. Conclusion Cyclo Mix seems to be a safe therapy that effectively reduces the IOP and glaucoma medications in eyes with uncontrolled open-angle glaucoma for up to 6 months. How to cite this article Waldo L-G, Julio H-Q, Jennifer C-V, et al. Combined Technique for the Application of Micropulse Cyclophotocoagulation in Patients with Uncontrolled Glaucoma: Cyclo Mix. J Curr Glaucoma Pract 2020;14(3):93–97.

The effect of cumulative energy in repeated subliminal transscleral cyclophotocoagulation: a retrospective study

“…The guidelines [ 24 , 27 ] provide a useful collection of evidence-based consensus mainly on the MicroPulse (IRIDEX) machine. On the other hand, data regarding the safety and the efficacy of the Supra 810 and Vitra 810 (Quantel Medical) machines are scarce [ 37 , 39 , 50 , 51 ]. Our results suggest that similar outcomes can be achieved with the Quantel machines, also broadening treatment options.…”

MicroPulse Transscleral Laser Therapy Demonstrates Similar Efficacy with a Superior and More Favorable Safety Profile Compared to Continuous-Wave Transscleral Cyclophotocoagulation

“…MP-TLT demonstrated much better results than the recently introduced “Cyclo Mix” technique, performed using the Supra 810 nm SubLiminal® laser (Quantel Medical, Cournon d'Auvergne, France). A study by Waldo et al reported an absolute success rate of only 30.4% and a relative one of 87% [ 53 ]. The study presented, however, a limited number of participants (23 eyes from 13 patients) and comes with the disadvantages regarding safety due to CW-TSCPC compared to MP-TLT alone.…”