Combined sterile insect technique and incompatible insect technique: The first proof-of-concept to suppress Aedes aegypti vector populations in semi-rural settings in Thailand

Kittayapong, Pattamaporn; Ninphanomchai, Suwannapa; Limohpasmanee, Wanitch; Chansang, Chitti; Chansang, Uruyakorn; Mongkalangoon, Piti

doi:10.1371/journal.pntd.0007771

Cited by 102 publications

(115 citation statements)

References 51 publications

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“…It follows that releasing an excess of Wolbachia-infected male mosquitoes will undermine a program by increasing the potential number of females accidentally released, while increasing the demand on rearing facilities. This is particularly the case as the first area-wide SIT/IIT programs have typically employed a constant or increasing release rate over time (Kittayapong et al, 2019, Crawford et al, 2020. If the rate at which females are mated is density-independent and only the mate type is density-dependent (as we have assumed in our model), then very high overflooding ratios hold little strategic value over moderate ones.…”

Section: Discussionmentioning

confidence: 99%

Modelling theWolbachiaIncompatible Insect Technique: strategies for effective mosquito population elimination

Pagendam

Trewin

Johnson³

et al. 2020

Preprint

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The Wolbachia Incompatible Insect Technique (IIT) shows promise as a method for eliminating invasive mosquitoes such as Aedes aegypti (Linnaeus)(Diptera: Culicidae) and reducing the incidence of vector-borne diseases such as dengue, chikungunya and Zika. Successful implementation of this biological control strategy relies on high-fidelity separation of male from female insects in mass production systems for inundative release into landscapes. Processes for sex-separating mosquitoes are typically error prone, laborious and IIT programs run the risk of releasing Wolbachia infected females and replacing wild mosquito populations. We introduce a simple Markov Population Process (MPP) model for studying mosquito populations subjected to a Wolbachia-IIT program which exhibit an unstable equilibrium threshold. The model is used to study, in silico, scenarios that are likely to yield a successful elimination result. Our results suggest that elimination is best achieved by releasing males at rates that adapt to the ever-decreasing wild population, thus reducing the risk of releasing Wolbachia-infected females while reducing costs. While very high-fidelity sex-separation is required to avoid establishment, release programs tend to be robust to the release of a small number of Wolbachia-infected females. These findings will inform and enhance the next generation of Wolbachia-IIT control strategies that are already showing great promise in field trials.

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Section: Discussionmentioning

confidence: 99%

Modelling theWolbachiaIncompatible Insect Technique: strategies for effective mosquito population elimination

Pagendam

Trewin

Johnson³

et al. 2020

Preprint

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“…As Z. cucurbitae larvae largely feed inside fruits, they have long been notoriously difficult to be controlled by insecticides that are commonly used for controlling many pests and diseases. Thus, there is a need to carry out studies on basic insect biology and to develop new management strategies for better controlling it, for example, genetic control and sterile insect technique (SIT) ( Du et al 2019 , Kittayapong et al 2019 ). SIT acts by releasing a large number of sterile males that can compete with wild-type males to mate with females into the environment, making the females in the natural population to produce no offspring and thereby decreasing the target population ( Klassen and Curtis 2005 , Thistlewood and Judd 2019 ).…”

mentioning

confidence: 99%

A Novel Solid Artificial Diet for Zeugodacus cucurbitae (Diptera: Tephritidae) Larvae With Fitness Parameters Assessed by Two-Sex Life Table

Liu

Lin

et al. 2020

Journal of Insect Science

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The melon fly, Zeugodacus cucurbitae (Coquillett), is a serious pest of many fruits and vegetables throughout the world. Here we have developed an easy and quick-to-prepare solid medium with multiple benefits including reductions in post-rearing waste, storage space, and labor for rearing Z. cucurbitae larvae. The development time from egg to pupa was 19.11 d when larvae were reared on the artificial diet, slightly longer than 17.73 d on pumpkin and 17.13 d on cucumber. Zeugodacus cucurbitae achieved higher values of pupal weight, length, and width on the artificial diet than two natural diet controls. The rates of pupation and adult emergence of Z. cucurbitae grown on the solid medium were comparable with those on pumpkin and cucumber. Furthermore, determined by age-specific two-sex life table method, the age-specific survival rate of Z. cucurbitae was higher on the artificial diet than cucumber but lower than pumpkin. The reproductive ability and population dynamics of Z. cucurbitae were not significantly affected on the solid medium compared with those on the two natural diets. The results suggest that our solid artificial diet is excellent for rearing Z. cucurbitae larvae in laboratory and may be used for its mass rearing, therefore facilitating its research and control.

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“…After copulation, this dominant gene causes the death of its progeny. These approaches show a great potential for disease control (79,80) and have been tested in different endemic countries for A. aegypti control (81)(82)(83)(84). In Brazil, the use of OX513A self-limiting strain reduced the local A. aegypti population by up to 95% in a suburb of Juazeiro, Bahia (85).…”

Section: Immunoprophylactic and Biological Control Approachesmentioning

confidence: 99%

Historical Perspective and Biotechnological Trends to Block Arboviruses Transmission by Controlling Aedes aegypti Mosquitos Using Different Approaches

et al. 2020

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Continuous climate changes associated with the disorderly occupation of urban areas have exposed Latin American populations to the emergence and reemergence of arboviruses transmitted by Aedes aegypti. The magnitude of the financial and political problems these epidemics may bring to the future of developing countries is still ignored. Due to the lack of effective antiviral drugs and vaccines against arboviruses, the primary measure for preventing or reducing the transmission of diseases depends entirely on the control of vectors or the interruption of human-vector contact. In Brazil the first attempt to control A. aegypti took place in 1902 by eliminating artificial sites of eproduction. Other strategies, such as the use of oviposition traps and chemical control with dichlorodiphenyltrichlorethane and pyrethroids, were successful, but only for a limited time. More recently, biotechnical approaches, such as the release of transgenics or sterile mosquitoes and the, development of transmission blocking vaccines, are being applied to try to control the A. aegypti population and/or arbovirus transmission. Endemic countries spend about twice as much to treat patients as they do on the prevention of mosquito-transmitted diseases. The result of this strategy is an explosive outbreak of arboviruses cases. This review summarizes the social impacts caused by A. aegypti-transmitted diseases, mainly from a biotechnological perspective in vector control aimed at protecting Latin American populations against arboviruses.

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Combined sterile insect technique and incompatible insect technique: The first proof-of-concept to suppress Aedes aegypti vector populations in semi-rural settings in Thailand

Cited by 102 publications

References 51 publications

Modelling theWolbachiaIncompatible Insect Technique: strategies for effective mosquito population elimination

Modelling theWolbachiaIncompatible Insect Technique: strategies for effective mosquito population elimination

A Novel Solid Artificial Diet for Zeugodacus cucurbitae (Diptera: Tephritidae) Larvae With Fitness Parameters Assessed by Two-Sex Life Table

Historical Perspective and Biotechnological Trends to Block Arboviruses Transmission by Controlling Aedes aegypti Mosquitos Using Different Approaches

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