Combined pulsed-dye laser and medical therapy for treatment of cutaneous sarcoidosis lesions: a case report

Abstract

Sarcoidosis is a systemic granulomatous disease of unknown etiology that most frequently occurs in the lungs. However, cutaneous lesions are often the primary sign. Cutaneous sarcoidosis is difficult to treat, although different therapies have been applied. We herein report a case in which cutaneous sarcoidosis was treated with pulsed-dye laser (PDL) therapy along with oral administration of acitretin and hydroxychloroquine; no topical medications were applied. All patient details are de-identified. The treatment areas gradually improved after several courses of PDL therapy. This case illustrates that PDL therapy can serve as an auxiliary treatment for cutaneous sarcoidosis.

Cutaneous Sarcoidosis Induced by Laser Therapy: Case Report and Review of the Literature

“…While the existing literature discusses the treatment of cutaneous sarcoidosis with laser therapy [ 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 ] ( Table 1 ), there are also singular occurrences describing laser therapy causing cutaneous sarcoidosis [ 36 , 37 ] ( Table 2 ).…”

“…Dong et al [ 25 ] reported a 46-year-old Asian woman with longstanding left facial lesions, diagnosed with cutaneous sarcoidosis. Treatment included acitretin (10 mg q.d.…”

“…While the existing literature discusses the treatment of cutaneous sarcoidosis with laser therapy [23][24][25][26][27][28][29][30][31][32][33][34][35] (Table 1), there are also singular occurrences describing laser therapy causing cutaneous sarcoidosis [36,37] (Table 2). The Pulsed Dye Laser (PDL) was designed with the objective of implementing selective thermolysis for vascular lesions, with hemoglobin serving as the principal chromophore.…”

“…Fractionated Pulsed Dye Laser (FPDL) treatment resulted in complete clearance at treated sites after 4 weeks, contrasting with untreated sites. Dong et al [25] reported a 46-year-old Asian woman with longstanding left facial lesions, diagnosed with cutaneous sarcoidosis. Treatment included acitretin (10 mg q.d.…”

Passively Q‐switched operation of Yb,Ho:LuVO4 laser with a semiconductor saturable absorber mirrors

“…Pulsed solid‐state lasers operated at around 2 µm range to have great significance for the absorption peak of water molecules and human issue which have many application including laser lidar, 1,2 optoelectrionic countermeasure, 3–7 laser minimally invasive surgery, 8 and environmental monitoring, 9 and so on. In addition, 2 µm pulsed lasers are efficient pump sources for nonlinear optical frequency conversion in the range of 3–12 µm 10,11 .…”