Combined pulmonary lobectomy for surgical treatment of a malignant fibrous histiocytoma of the chest wall: a case report

Liu, Yi; Chen, Gang; Wu, Yi Lin; Liu, Renwang; Xu, Song; Chen, Jun; Zhou, Qinghua

doi:10.1186/1746-1596-9-21

Cited by 4 publications

(3 citation statements)

References 12 publications

(11 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Malignant fibrous histiocytomas uncommonly manifest as primary chest wall neoplasms. In this location, the ETF, subcutaneous soft tissue, and skeletal muscle are usually involved (70,71).…”

Section: Neoplasmsmentioning

confidence: 99%

Multidetector CT for Evaluation of the Extrapleural Space

et al. 2017

View full text Add to dashboard Cite

The extrapleural space (EPS) is an anatomic space at the periphery of the chest that can be involved in a number of disease processes. This space lies between the inner surface of the ribs and the parietal pleura and contains adipose tissue, loose connective tissue, lymph nodes, vessels, endothoracic fascia, and the innermost intercostal muscle. It is often overlooked on cross-sectional imaging studies and almost invariably overlooked on conventional radiographic studies. At conventional radiography, the EPS occasionally can be seen when there is extrapleural fat proliferation, which might be confused with pleural thickening or pleural effusion. Knowledge of the normal anatomy of the EPS depicted at computed tomography (CT) and of the relationship of the EPS with parenchymal, pleural, and chest wall processes is key to the detection of extrapleural abnormalities. Disease entities that most commonly affect the EPS include chronic inflammatory disorders, infection, trauma, and neoplasms. Chronic inflammatory conditions and infectious processes of the lungs and pleurae induce adipocyte proliferation adjacent to the inflamed tissue, resulting in increased extrapleural fat. Chest wall trauma with extrapleural hematoma formation causes characteristic CT findings that enable differentiation of the extrapleural hematoma from hemothorax and warrant a different treatment approach. Extrapleural air is commonly seen in patients with pneumomediastinum and should be distinguished from pneumothorax because it requires a different treatment approach. Intrathoracic neoplasms can cause an increase in the attenuation of normal extrapleural fat owing to pleural inflammation, lymphatic obstruction, lymphangitic spread, or direct invasion by tumor. The normal and pathologic appearances of the EPS, as depicted at thoracic CT, and the differential diagnosis of findings in the EPS are reviewed. RSNA, 2017.

show abstract

“…Malignant fibrous histiocytomas uncommonly manifest as primary chest wall neoplasms. In this location, the ETF, subcutaneous soft tissue, and skeletal muscle are usually involved (70,71).…”

Section: Neoplasmsmentioning

confidence: 99%

Multidetector CT for Evaluation of the Extrapleural Space

et al. 2017

View full text Add to dashboard Cite

show abstract

“…The prognostic factors known to be associated with survival in malignant fibrous histiocytoma patients include tumor stage, depth, tumor size, presence of metastasis, patient age and histological subtype. [ 7 ] Our patient had nearly all the unfavorable prognostic factors: an elderly man with comorbidities, a big deepseated tumor with high stage (Stage IIIB according to 8th Edition of the American Joint Committee on Cancer Staging System for Soft Tissue Sarcoma of the Trunk and Extremities), but he is still alive although he had recurrence. [ 8 ]…”

Section: Discussionmentioning

confidence: 99%

A rare giant sarcoma of the chest wall: Undifferentiated pleomorphic sarcoma

Kocaman¹,

Yenigün²,

Kaya³

et al. 2021

Turk Gogus Kalp Dama

View full text Add to dashboard Cite

Undifferentiated pleomorphic sarcoma or, as formerly called, malignant fibrous histiocytoma is a type of sarcoma which originates from fibroblast and histiocytic cells. It is the most common type of sarcoma among all soft tissue sarcomas in adults. Its most common site is the lower limb, followed by the upper limb and the retroperitoneum. It is rarely encountered on chest wall. In the differential diagnosis of masses on chest wall, it is important to consider undifferentiated pleomorphic sarcoma in surgical planning. In this article, we report a male case with a giant undifferentiated pleomorphic sarcoma located above the right scapula.

show abstract

“…Its predilection sites are the trunk part of extremities and the deep musculature of the retroperitoneum ( 3 ). Although the lung is the most common site of MFH metastasis (75%), MFH originating in the lung is extremely rare ( 4 ). On account of its complex and heterogeneous pathological characteristics, lack of specific immunohistochemical markers and no lineage specificity, it is difficult for pathologists to agree on a standard for MFH tumor evaluation ( 5 ).…”

Section: Introductionmentioning

confidence: 99%

Primary giant cell malignant fibrous histiocytoma of the lung: a rare case report and literature review

Xu¹,

Qu²,

Yu³

2020

Transl Cancer Res TCR

View full text Add to dashboard Cite

Malignant fibrous histiocytoma (MFH) usually involves the extremities. Among MFH, primary giant cell malignant fibrous histiocytoma of the lung is extremely rare, with nonspecific symptoms. A 45-year-old woman was first diagnosed as sclerosing hemangioma due to long-term persistent cough and blood in sputum. One year later, the condition became worse and hemoptysis occurred. At the second visit, the same mass was found to be larger than the previous one. Lobectomy was performed and the primary giant cell MFH of the lung was confirmed. Renal and sacrum metastasis occurred six months after operation.The efficacy of hypofractionation radiotherapy and immuno targeted follow-up therapy is significant. At present, there is no standard treatment plan. For the patients in the early stage, surgical resection is the main treatment method; but for the patients in the middle and late stage, the treatment is relatively single. So early diagnosis and treatment are particularly important, In this paper, we first report the use of pembrolizumab combined with anlotinib in a patient with advanced giant cell MFH of the lung, with failure of routine treatment. The development of the disease had successfully delayed and satisfactory results were observed. Therefore, it is very necessary to emphasize the choice of treatment plan to improve the prognosis of patients.

show abstract

Combined pulmonary lobectomy for surgical treatment of a malignant fibrous histiocytoma of the chest wall: a case report

Cited by 4 publications

References 12 publications

Multidetector CT for Evaluation of the Extrapleural Space

Multidetector CT for Evaluation of the Extrapleural Space

A rare giant sarcoma of the chest wall: Undifferentiated pleomorphic sarcoma

Primary giant cell malignant fibrous histiocytoma of the lung: a rare case report and literature review

Contact Info

Product

Resources

About